Synthetic ligand-coated magnetic nanoparticles for microfluidic bacterial separation from blood

JJ Lee, KJ Jeong, M Hashimoto, AH Kwon, A Rwei… - Nano …, 2014 - ACS Publications
Bacterial sepsis is a serious clinical condition that can lead to multiple organ dysfunction
and death despite timely treatment with antibiotics and fluid resuscitation. We have …

[HTML][HTML] Nanoparticle targeting of Gram-positive and Gram-negative bacteria for magnetic-based separations of bacterial pathogens

HD Lu, SS Yang, BK Wilson, SA McManus… - Applied …, 2017 - Springer
Antimicrobial resistance is a healthcare problem of increasing significance, and there is
increasing interest in developing new tools to address bacterial infections. Bacteria-targeting …

Homogeneous distribution of magnetic, antimicrobial-carrying nanoparticles through an infectious biofilm enhances biofilm-killing efficacy

K Quan, Z Zhang, Y Ren, HJ Busscher… - ACS Biomaterials …, 2019 - ACS Publications
Magnetic, antimicrobial-carrying nanoparticles provide a promising, new and direly needed
antimicrobial strategy against infectious bacterial biofilms. Penetration and accumulation of …

Bacterial inactivation using silver-coated magnetic nanoparticles as functional antimicrobial agents

L Wang, J Luo, S Shan, E Crew, J Yin… - Analytical …, 2011 - ACS Publications
The ability for silver nanoparticles to function as an antibacterial agent while being
separable from the target fluids is important for bacterial inactivation in biological fluids. This …

Bioconjugated magnetic nanoparticles for the detection of bacteria

YW Chu, DA Engebretson… - Journal of biomedical …, 2013 - ingentaconnect.com
Blood culture is traditionally a time-consuming method and has not changed significantly in
several decades. Using nanotechnology, such as the use of magnetic nanoparticles (MNPs) …

Artificial channels in an infectious biofilm created by magnetic nanoparticles enhanced bacterial killing by antibiotics

K Quan, Z Zhang, H Chen, X Ren, Y Ren, BW Peterson… - Small, 2019 - Wiley Online Library
The poor penetrability of many biofilms contributes to the recalcitrance of infectious biofilms
to antimicrobial treatment. Here, a new application for the use of magnetic nanoparticles in …

3D-printed microfluidic magnetic preconcentrator for the detection of bacterial pathogen using an ATP luminometer and antibody-conjugated magnetic nanoparticles

C Park, J Lee, Y Kim, J Kim, J Lee, S Park - Journal of microbiological …, 2017 - Elsevier
Various types of microfluidic systems have been developed to detect bacterial pathogens.
However, most of these require enrichment steps that take at least several hours when …

Micromagnetic–microfluidic blood cleansing device

CW Yung, J Fiering, AJ Mueller, DE Ingber - Lab on a Chip, 2009 - pubs.rsc.org
Sepsis is a lethal disease caused by a systemic microbial infection that spreads via the
bloodstream to overwhelm the body's defenses. Current therapeutic approaches are often …

Magnetic glyco-nanoparticles: a unique tool for rapid pathogen detection, decontamination, and strain differentiation

K El-Boubbou, C Gruden, X Huang - Journal of the American …, 2007 - ACS Publications
Many pathogens use mammalian cell surface carbohydrates as anchors for attachments,
which subsequently results in infection. The unique combination of magnetic nanoparticles …

[HTML][HTML] Applications of iron oxide-based magnetic nanoparticles in the diagnosis and treatment of bacterial infections

C Xu, OU Akakuru, J Zheng, A Wu - Frontiers in bioengineering and …, 2019 - frontiersin.org
Diseases caused by bacterial infections, especially drug-resistant bacteria have seriously
threatened human health throughout the world. It has been predicted that antimicrobial …