BMP signaling plays an important role in dentin development. BMPs and antagonists
regulate odontoblast differentiation and downstream gene expression via canonical Smad …

Several Bmp genes are expressed in the developing mouse tooth germ from the initiation to
the late-differentiation stages, and play pivotal roles in multiple steps of tooth development …

It is known that stem cells from exfoliated deciduous teeth (SHED) can be induced to
differentiate into odontoblasts. However, the nature of dentin-derived morphogenic signals …

During the phase of overt tooth cytodifferentiation that occurs after birth in the mouse and
using the 3.6 Collagen1a-Cre and the BMP4 floxed and BMP4 knockout mice, the BMP4 …

Dentin sialophosphoprotein (DSPP), a typical dentin-specific protein, is mainly expressed in
the dentin extracellular matrix and plays a role in dentin mineralization. BMP-2 provides a …

Tooth development is regulated by sequential and reciprocal epithelium-mesenchymal
interactions and their related molecular signaling pathways, such as bone morphogenetic …

Tooth development is regulated by epithelial-mesenchymal interactions and their reciprocal
molecular signaling. Bone morphogenetic protein 2 (Bmp2) is essential for tooth formation …

INTRODUCTION: Bone morphogenetic protein-2 (BMP-2) is a member of the transforming
growth factor-β (TGF-β) superfamily, which has a broad range of activities that affect many …

Formation of highly organized dental hard tissues is a complex process involving sequential
and ordered deposition of an extracellular scaffold, followed by its mineralization …

BMP signaling is one of the key pathways regulating craniofacial development. It is involved
in the early patterning of the head, the development of cranial neural crest cells, and facial …