A long-standing mystery in the field of Polycomb and Trithorax regulation is how these
proteins, which are highly conserved between flies and mammals, can regulate several …

Polycomb/Trithorax group response elements (PRE/TREs) are fascinating chromosomal
pieces. Just a few hundred base pairs long, these elements can remember and maintain the …

Abstract Background Polycomb/Trithorax response elements (PREs) are cis-regulatory
elements essential for the regulation of several hundred developmentally important genes …

Polycomb response elements (PREs) are specific DNA sequences that stably maintain the
developmental pattern of gene expression. Drosophila PREs are well characterized …

Polycomb/Trithorax response elements (PRE/TREs) maintain transcriptional decisions to
ensure correct cell identity during development and differentiation. There are thought to be …

The Polycomb (PcG) and Trithorax (TrxG) proteins are epigenetic regulators that maintain
correct expression patterns of several hundred developmentally important genes by binding …

cis-Regulatory DNA elements contain multiple binding sites for activators and repressors of
transcription. Among these elements are enhancers, which establish gene expression …

Polycomb/Trithorax response elements (PRE/TREs) can switch their function reversibly
between silencing and activation by mechanisms that are poorly understood. Here we show …

In Drosophila, Polycomb (PcG) and Trithorax (TrxG) group proteins are assembled on
Polycomb response elements (PREs) to maintain tissue and stage-specific patterns of gene …

Polycomb and Trithorax group proteins maintain stable epigenetic memory of gene
expression states for some genes, but many targets show highly dynamic regulation. Here …