This review seeks to address 10 essential questions regarding the clinical use of local
anaesthetics. Each local anaesthetic has distinctive physicochemical properties but with the …

Research into local anaesthetic mechanisms over the past few years has focused on two
main issues. First, attention has focused on development of compounds with fewer side …

Update on local anesthetics : Current Opinion in Anesthesiology Update on local anesthetics :
Current Opinion in Anesthesiology Log in or Register Subscribe to journalSubscribe Get new …

Highlights•Local anesthetics are currently known to be not only sodium channel blockers but
also blockers of many different receptors.•New short-acting local anesthetics have a …

These are heady days for the regional anesthesia community. Ultrasound technology and
continuous-infusion catheters hold the promise for increasing the popularity and utility of …

Local anesthetics have been used clinically for more than a century, but new insights into
their mechanisms of action and their interaction with biological systems continue to surprise …

Local anesthetics are among the most widely used drugs. Their development over the past
century ranges from a documented influence on Freud's Interpretation of Dreams 1 to the …

Local anaesthetics are responsible for 5 to 10% of all reported adverse reactions to
anaesthetic drugs. Adverse effects may be classified as:(a) those associated directly with …

REGIONAL anesthesia has evolved in recent years from a technique into an art, practiced by
some pioneering anesthesiologists. As with any art form, regional anesthesia has obtained a …

Local anesthetics : Current Opinion in Anesthesiology Local anesthetics : Current Opinion in
Anesthesiology Log in or Register Subscribe to journalSubscribe Get new issue alertsGet alerts …