Antimicrobial exposures in critically ill patients receiving extracorporeal membrane oxygenation

K Shekar, MH Abdul-Aziz, V Cheng… - American journal of …, 2023 - atsjournals.org
Rationale: Data suggest that altered antimicrobial concentrations are likely during
extracorporeal membrane oxygenation (ECMO). Objectives: The primary aim of this analysis …

Pharmacokinetics of commonly used antimicrobials in critically ill adults during extracorporeal membrane oxygenation: a systematic review

MA Duceppe, S Kanji, AT Do, N Ruo, YA Cavayas… - Drugs, 2021 - Springer
Purpose Adequate dosing of antimicrobials is critical to properly treat infections and limit
development of resistance and adverse effects. Limited guidance exists for antimicrobial …

Practices surrounding antimicrobial use in patients managed with extracorporeal membrane oxygenation: An international survey

A Dilawri, J Muir, D Brodie, D Abrams, C Agerstrand… - Journal of Critical …, 2024 - Elsevier
Purpose This study aimed to survey critical care clinicians and characterize their perception
of antimicrobial dosing strategies in patients receiving extracorporeal membrane …

Pharmacokinetic changes of antibiotic, antiviral, antituberculosis and antifungal agents during extracorporeal membrane oxygenation in critically ill adult patients

J Hahn, JH Choi, MJ Chang - Journal of Clinical Pharmacy and …, 2017 - Wiley Online Library
What is known and objective Extracorporeal membrane oxygenation (ECMO) is a life‐saving
system used for critically ill patients with cardiac and/or respiratory failure. The …

Machines that help machines to help patients: optimising antimicrobial dosing in patients receiving extracorporeal membrane oxygenation and renal replacement …

JA Roberts, R Bellomo, MO Cotta, BCP Koch… - Intensive Care …, 2022 - Springer
Intensive care unit (ICU) patients with end-organ failure will require specialised machines or
extracorporeal therapies to support the failing organs that would otherwise lead to death …

Antibiotic dosing during extracorporeal membrane oxygenation: does the system matter?

MH Abdul-Aziz, JA Roberts - Current Opinion in Anesthesiology, 2020 - journals.lww.com
An advanced understanding of the pharmacokinetic alterations in critically ill patients
receiving ECMO is essential to provide optimal antibiotic dosing in these complex patients …

Pharmacokinetics and dosing of anti-infective drugs in patients on extracorporeal membrane oxygenation: a review of the current literature

J Sherwin, T Heath, K Watt - Clinical therapeutics, 2016 - Elsevier
Purpose Extracorporeal membrane oxygenation (ECMO) is a cardiopulmonary bypass
device that is used to temporarily support the most critically ill of patients with respiratory …

Antifungal dosing in critically ill patients on extracorporeal membrane oxygenation

H Lyster, K Shekar, K Watt, A Reed, JA Roberts… - Clinical …, 2023 - Springer
Extracorporeal membrane oxygenation (ECMO) is an established advanced life support
system, providing temporary cardiac and/or respiratory support in critically ill patients …

Reducing broad-spectrum antimicrobial use in extracorporeal membrane oxygenation: reduce AMMO study

A Shah, P Sampathkumar, RW Stevens… - Clinical Infectious …, 2021 - academic.oup.com
Background The use of extracorporeal membrane oxygenation (ECMO) in critically ill adults
is increasing. There are currently no guidelines for antimicrobial prophylaxis. We analyzed 7 …

Nosocomial infections during extracorporeal membrane oxygenation

M Martínez-Martínez, FX Nuvials… - Current Opinion in Critical …, 2022 - journals.lww.com
ECMO is a rescue therapy for severe hemodynamic or respiratory failure. Nosocomial
infections on ECMO support are frequent (infection rate ranging between 20.5% to more …