Microbiology: and Amoebophilus invented the machine gun!

E Cascales - Current Biology, 2017 - cell.com
Bacterial contractile injection systems are fascinating particles that use a spring-like
mechanism to inject an effector-loaded needle into target cells. A recent study shows that the …

How well can an amoeba climb?

Y Fukui, TQP Uyeda, C Kitayama… - Proceedings of the …, 2000 - National Acad Sciences
We report here our efforts to measure the crawling force generated by cells undergoing
amoeboid locomotion. In a centrifuge microscope, acceleration was increased until …

Locomotion of Physarum polycephalum amoebae is guided by a short range interaction with E. coli

DN Jacobson - Experimental Cell Research, 1980 - Elsevier
Studies of the behavior of Physarum polycephalum amoebae have shown that locomotion of
these cells is guided by surfaces composed of aggregated bacteria. Amoebae move readily …

Retraction in amoeboid cell motility powered by cytoskeletal dynamics

L Miao, O Vanderlinde, M Stewart, TM Roberts - Science, 2003 - science.org
Cells crawl by coupling protrusion of their leading edge with retraction of their cell body.
Protrusion is generated by the polymerization and bundling of filaments, but the mechanism …

Engineering an artificial amoeba propelled by nanoparticle-triggered actin polymerization

J Yi, J Schmidt, A Chien, CD Montemagno - Nanotechnology, 2009 - iopscience.iop.org
We have engineered an amoeba system combining nanofabricated inorganic materials with
biological components, capable of propelling itself via actin polymerization. The …

In situ architecture, function, and evolution of a contractile injection system

D Böck, JM Medeiros, HF Tsao, T Penz, GL Weiss… - Science, 2017 - science.org
Contractile injection systems mediate bacterial cell-cell interactions by a bacteriophage tail–
like structure. In contrast to extracellular systems, the type 6 secretion system (T6SS) is …

Dissection of amoeboid movement into two mechanically distinct modes

K Yoshida, T Soldati - Journal of cell science, 2006 - journals.biologists.com
The current dominant model of cell locomotion proposes that actin polymerization pushes
against the membrane at the leading edge producing filopodia and lamellipodia that move …

Forces generated during actin-based propulsion: a direct measurement by micromanipulation

Y Marcy, J Prost, MF Carlier… - Proceedings of the …, 2004 - National Acad Sciences
Dynamic actin networks generate forces for numerous types of movements such as
lamellipodia protrusion or the motion of endocytic vesicles. The actin-based propulsive …

A bacterial phage tail-like structure kills eukaryotic cells by injecting a nuclease effector

I Rocchi, CF Ericson, KE Malter, S Zargar, F Eisenstein… - Cell reports, 2019 - cell.com
Many bacteria interact with target organisms using syringe-like structures called contractile
injection systems (CISs). CISs structurally resemble headless bacteriophages and share …

Harnessing Motile Amoeboid Cells as Trucks for Microtransport and‐Assembly

O Nagel, M Frey, M Gerhardt, C Beta - Advanced Science, 2019 - Wiley Online Library
Cell‐driven microtransport is one of the most prominent applications in the emerging field of
biohybrid systems. While bacterial cells have been successfully employed to drive the …