[HTML][HTML] Fundamental advances in hydrogels for the development of the next generation of smart delivery systems as biopharmaceuticals

N Nassar, S Kasapis - International Journal of Pharmaceutics, 2023 - Elsevier
Recent advances in developing and applying therapeutic peptides for anticancer,
antimicrobial and immunomodulatory remedies have opened a new era in therapeutics. This …

[HTML][HTML] A review on recent advances in stabilizing peptides/proteins upon fabrication in hydrogels from biodegradable polymers

F Raza, H Zafar, Y Zhu, Y Ren, A -Ullah, AU Khan… - Pharmaceutics, 2018 - mdpi.com
Hydrogels evolved as an outstanding carrier material for local and controlled drug delivery
that tend to overcome the shortcomings of old conventional dosage forms for small drugs …

Peptide gels for controlled release of proteins

G Uzunalli, MO Guler - Therapeutic delivery, 2020 - Taylor & Francis
Treatment strategies in clinics have been shifting from small molecules to protein drugs due
to the promising results of a highly specific mechanism of action and reduced toxicity …

Thermo-responsive hydrogels for cancer local therapy: Challenges and state-of-art

D Rafael, MMR Melendres, F Andrade… - International journal of …, 2021 - Elsevier
Despite the enormous efforts done by the scientific community in the last decades, advanced
cancer is still considered an incurable disease. New formulations are continuously under …

Emerging hydrogel designs for controlled protein delivery

KH Bae, M Kurisawa - Biomaterials Science, 2016 - pubs.rsc.org
Hydrogels have evolved into indispensable biomaterials in the fields of drug delivery and
regenerative medicine. This minireview aims to highlight the recent advances in the …

[HTML][HTML] Stimuli-Responsive Hydrogels for Protein Delivery

R Malta, AC Marques, PC Costa, MH Amaral - Gels, 2023 - mdpi.com
Proteins and peptides are potential therapeutic agents, but their physiochemical properties
make their use as drug substances challenging. Hydrogels are hydrophilic polymeric …

Review of recent advances and their improvement in the effectiveness of hydrogel-based targeted drug delivery: a hope for treating cancer

M Sonker, S Bajpai, MA Khan, X Yu… - ACS Applied Bio …, 2021 - ACS Publications
Using hydrogels for delivering cancer therapeutics is advantageous in pharmaceutical
usage as they have an edge over traditional delivery, which is tainted due to the risk of …

[HTML][HTML] Hydrogel biomaterials for drug delivery: Mechanisms, design, and drugs

W Nafo - Hydrogels-from tradition to innovative platforms with …, 2022 - intechopen.com
Due to their unique physical and chemical properties, hydrogels have attracted significant
attention in several medical fields, specifically, drug delivery applications in which gel-based …

In search of bioinspired hydrogels from amphiphilic peptides: a template for nanoparticle stabilization for the sustained release of anticancer drugs

RR Mehra, P Tiwari, A Basu, A DuttKonar - New Journal of Chemistry, 2019 - pubs.rsc.org
The development of potent stimuli-responsive hydrogels has rapidly expanded in the last
decades due to their diversified applications in the field of biomedicines. In accordance with …

Hydrogels with smart systems for delivery of hydrophobic drugs

D Gu, AJ O'Connor, G GH Qiao… - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: Smart hydrogel systems present opportunities to not only provide hydrophobic
molecule encapsulation capability but to also respond to specific delivery routes. Areas …