IN THE recent past, some of the mechanisms have been unraveled which produce the
characteristic heterogeneity of shape and function among the newly generated follicles …

Functional and morphologic heterogeneity of human multinodular goiters was investigated
in 300 samples from" cold" and" hot" regions of 20 goiters transplanted onto nude mice …

The prominent characteristics of euthyroid and hyperthyroid human nodular goiters are the
regional variability of iodine metabolism and the appearence of “hot” autonomous follicles …

This study was aimed at dissecting the cellular mechanisms that underly the growth of
actively expanding human goiter nodules. Thirty-two nodules from different patients, all …

Toxic nodular goitre is the late result of a slow growth process generating new daughter
follicles from the mother follicles of a normal thyroid gland. Since the normal follicular shell is …

Autoradiographic studies of the thyroids of 21 patients with a gross autonomous functioning
nodule demonstrated similar small or micronodules in 76%. They were also present in 4 …

Thirty-nine thyroid nodules, removed because of recent growth, were analyzed
morphologically by serial histological sections for the classical histomorphological hallmarks …

668 DUMONT, LAMY, ROGER, AND MAENHAUT Volume 72 roid weighs-0.2 g at 20-25 wk
in the fetus and-15 g in the adult and assuming a grossly similar tissue composition, this …

IN THE past two decades, research on simple goiter has concentrated on the mechanisms
which govern the adaptation of the thyroid gland to iodine deficiency. As a result of these …

Pathogenesis of nodule formation was studied in over 100 nodular goiters from a
subendemic area. 60 surgical specimens were autoradiographed. Only one classical, well …