Efficacy and safety of eslicarbazepine acetate monotherapy in patients converting from carbamazepine

L Pazdera, MR Sperling, JH Harvey, MC Sam… - …, 2018 - Wiley Online Library
Objective To evaluate the influence of prior use of carbamazepine (CBZ) and other
antiepileptic drugs (AED s) with a putatively similar mechanism of action (inhibition of …

[HTML][HTML] Safety, tolerability and effectiveness of transition to eslicarbazepine acetate from carbamazepine or oxcarbazepine in clinical practice

R Rocamora, J Peltola, G Assenza, R McMurray… - Seizure, 2020 - Elsevier
Purpose To assess the efficacy, safety and tolerability of eslicarbazepine acetate (ESL) in
patients transitioning from carbamazepine or oxcarbazepine to ESL in clinical practice, by …

Efficacy and safety of conversion to monotherapy with eslicarbazepine acetate in adults with uncontrolled partial‐onset seizures: a randomized historical‐control …

MR Sperling, J Harvey, T Grinnell, H Cheng, D Blum… - …, 2015 - Wiley Online Library
Objective To assess the efficacy and safety of eslicarbazepine acetate (ESL) as
monotherapy in North American patients with partial‐onset seizures (POS). Methods This …

Efficacy and safety of eslicarbazepine acetate versus controlled‐release carbamazepine monotherapy in newly diagnosed epilepsy: a phase III double‐blind …

E Trinka, E Ben‐Menachem, PA Kowacs, C Elger… - …, 2018 - Wiley Online Library
Objective We assessed the efficacy and safety of once‐daily eslicarbazepine acetate in
comparison with twice‐daily (BID) controlled‐release carbamazepine (carbamazepine‐CR) …

Conversion to eslicarbazepine acetate monotherapy: a pooled analysis of 2 phase III studies

MR Sperling, J French, MP Jacobson, L Pazdera… - Neurology, 2016 - AAN Enterprises
Objective: To assess the efficacy and safety of eslicarbazepine acetate (ESL) monotherapy.
Methods: This post hoc pooled analysis of 2 randomized double-blind studies (093-045 and …

Safety of Eslicarbazepine Acetate in Patients with Refractory Partial-Onset Seizures Treated With or Without Concomitant Carbamazepine: A Pooled Analysis of Three …

S Benbadis, V Biton, M Jacobson, E Trinka, M Carreño… - Neurology, 2014 - AAN Enterprises
OBJECTIVE: Investigate the safety of eslicarbazepine acetate (ESL) as adjunctive therapy
for partial-onset seizures (POS) with/without concomitant carbamazepine (CBZ) …

Efficacy of Eslicarbazepine Acetate in Patients with Refractory Partial-Onset Seizures Treated With or Without Concomitant Carbamazepine: A Pooled Analysis of …

S Chung, G Krauss, M Sperling, E Trinka, M Carreño… - Neurology, 2014 - AAN Enterprises
OBJECTIVE: Investigate the efficacy of eslicarbazepine acetate (ESL) as adjunctive therapy
for partial-onset seizures (POS) with/without concomitant carbamazepine (CBZ) …

Efficacy and safety of conversion to monotherapy with eslicarbazepine acetate in adults with uncontrolled partial-onset seizures: a historical-control phase III study

MP Jacobson, L Pazdera, P Bhatia, T Grinnell… - BMC neurology, 2015 - Springer
Abstract Background Eslicarbazepine acetate (ESL, Aptiom®) is a once-daily (QD)
anticonvulsant, approved as adjunctive treatment of partial-onset seizures (POS). It is …

Incidence of seizure exacerbation and seizures reported as adverse events during adjunctive treatment with eslicarbazepine acetate: a pooled analysis of three Phase …

M Carreño, S Benbadis, F Rocha, D Blum… - Epilepsia …, 2017 - Wiley Online Library
Objective To investigate whether adjunctive eslicarbazepine acetate (ESL) could lead to
exacerbation of seizures in some patients. Methods Post‐hoc analysis of data pooled from …

Long-term safety and efficacy of eslicarbazepine acetate in patients with focal seizures: results of the 1-year ESLIBASE retrospective study

V Villanueva, JM Serratosa, E Guillamón, M Garcés… - Epilepsy research, 2014 - Elsevier
Background Eslicarbazepine acetate (ESL) is a new antiepileptic drug (AED) licensed as
adjunctive therapy in adults with partial-onset or focal seizures. Objective To evaluate in a …