Modulation of Host Innate Immune Response in the Bladder by Uropathogenic Escherichia coli

BK Billips, SG Forrestal, MT Rycyk… - Infection and …, 2007 - Am Soc Microbiol
Uropathogenic Escherichia coli (UPEC), the most frequent cause of urinary tract infection
(UTI), is associated with an inflammatory response which includes the induction of …

Molecular Basis of Uropathogenic Escherichia coli Evasion of the Innate Immune Response in the Bladder

BK Billips, AJ Schaeffer, DJ Klumpp - Infection and immunity, 2008 - Am Soc Microbiol
In the urinary tract, the innate immune system detects conserved bacterial components and
responds to infection by activating the proinflammatory transcription factor NF-κB, resulting …

Suppression of Bladder Epithelial Cytokine Responses by Uropathogenic Escherichia coli

DA Hunstad, SS Justice, CS Hung, SR Lauer… - Infection and …, 2005 - Am Soc Microbiol
Urinary tract infections are most commonly caused by uropathogenic strains of Escherichia
coli (UPEC), which invade superficial bladder epithelial cells via a type 1 pilus-dependent …

[HTML][HTML] Subversion of Host Innate Immunity by Uropathogenic Escherichia coli

PD Olson, DA Hunstad - Pathogens, 2016 - mdpi.com
Uropathogenic Escherichia coli (UPEC) cause the majority of community-onset urinary tract
infections (UTI) and represent a major etiologic agent of healthcare-associated UTI …

Role of Uropathogenic Escherichia coli Virulence Factors in Development of Urinary Tract Infection and Kidney Damage

J Bien, O Sokolova, P Bozko - International journal of …, 2012 - Wiley Online Library
Uropathogenic Escherichia coli (UPEC) is a causative agent in the vast majority of urinary
tract infections (UTIs), including cystitis and pyelonephritis, and infectious complications …

Uropathogenic Escherichia coli virulence and innate immune responses during urinary tract infection

GC Ulett, M Totsika, K Schaale, AJ Carey… - Current opinion in …, 2013 - Elsevier
Urinary tract infections (UTI) are among the most common infectious diseases of humans
and are the most common nosocomial infections in the developed world. It is estimated that …

G‐CSF induction early in uropathogenic Escherichia coli infection of the urinary tract modulates host immunity

MA Ingersoll, KA Kline, HV Nielsen… - Cellular …, 2008 - Wiley Online Library
Uropathogenic Escherichia coli (UPEC), the causative agent of approximately 85% of
urinary tract infections (UTI), is a major health concern primarily affecting women. During …

Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages

NJ Bokil, M Totsika, AJ Carey, KJ Stacey, V Hancock… - Immunobiology, 2011 - Elsevier
Uropathogenic E. coli (UPEC) are the primary cause of urinary tract infections. Recent
studies have demonstrated that UPEC can invade and replicate within epithelial cells …

Uropathogen and host responses in pyelonephritis

L Schwartz, J de Dios Ruiz-Rosado… - Nature Reviews …, 2023 - nature.com
Urinary tract infections (UTIs) are among the most common bacterial infections seen in
clinical practice. The ascent of UTI-causing pathogens to the kidneys results in …

Uropathogenic Escherichia coli Engages CD14-Dependent Signaling to Enable Bladder-Macrophage-Dependent Control of Acute Urinary Tract Infection

AJ Carey, MJ Sullivan, BL Duell… - The Journal of …, 2016 - academic.oup.com
Background. CD14, a coreceptor for several pattern recognition receptors and a widely used
monocyte/macrophage marker, plays a key role in host responses to gram-negative …