Interfacial properties of pulmonary surfactant layers

R Wüstneck, J Perez-Gil, N Wüstneck, A Cruz… - Advances in colloid and …, 2005 - Elsevier
The composition of the pulmonary surfactant and the border conditions of normal human
breathing are relevant to characterize the interfacial behavior of pulmonary layers. Based on …

[PDF][PDF] Lateral phase separation in interfacial films of pulmonary surfactant

BM Discher, KM Maloney, WR Schief, DW Grainger… - Biophysical journal, 1996 - cell.com
To determine if lateral phase separation occurs in films of pulmonary surfactant, we used
epifluorescence microscopy and Brewster angle microscopy (BAM) to study spread films of …

Interfacial behaviour and mechanical properties of spread lung surfactant protein/lipid layers

N Wüstneck, R Wüstneck, VB Fainerman… - Colloids and Surfaces B …, 2001 - Elsevier
The surface behaviour of spread dipalmitoyl phosphatidyl choline (DPPC), lung surfactant
protein C (SP-C), and their mixtures were characterised using a captive bubble …

Pulmonary surfactant protein C containing lipid films at the air-water interface as a model for the surface of lung alveoli

A Post, AV Nahmen, M Schmitt, J Ruths… - Molecular Membrane …, 1995 - Taylor & Francis
The pulmonary surfactant lines as a complex monolayer of lipids and proteins the alveolar
epithelial surface. The monolayer dynamically adapts the surface tension of this interface to …

Monolayer–multilayer transitions in a lung surfactant model: IR reflection–absorption spectroscopy and atomic force microscopy

L Wang, P Cai, HJ Galla, H He, CR Flach… - European Biophysics …, 2005 - Springer
A hydrophobic pulmonary surfactant protein, SP-C, has been implicated in surface-
associated activities thought to facilitate the work of breathing. Model surfactant films …

Neutral lipids induce critical behavior in interfacial monolayers of pulmonary surfactant

BM Discher, KM Maloney, DW Grainger, CA Sousa… - Biochemistry, 1999 - ACS Publications
We have shown previously that lateral compression of pulmonary surfactant monolayers
initially induces separation of two phases but that these remix when the films become more …

[PDF][PDF] The structure of a model pulmonary surfactant as revealed by scanning force microscopy

A Von Nahmen, M Schenk, M Sieber, M Amrein - Biophysical journal, 1997 - cell.com
The structures formed by a pulmonary surfactant model system of
dipalmitoylphosphatidylcholine (DPPC), dipalmitoylphosphatidylglycerol (DPPG), and …

Lipid-protein interactions of hydrophobic proteins SP-B and SP-C in lung surfactant assembly and dynamics

J Pérez-Gil - Pediatric pathology & molecular medicine, 2001 - Taylor & Francis
Phospholipids have the major role in pulmonary surfactant concerning its biophysical
function of reducing surface tension at the alveolar air-liquid interface to facilitate respiratory …

[HTML][HTML] Role of pulmonary surfactant components in surface film formation and dynamics

EJA Veldhuizen, HP Haagsman - Biochimica et biophysica acta (bba) …, 2000 - Elsevier
Pulmonary surfactant is a mixture of lipids and proteins which is secreted by the epithelial
type II cells into the alveolar space. Its main function is to reduce the surface tension at the …

[PDF][PDF] Discrepancy between phase behavior of lung surfactant phospholipids and the classical model of surfactant function

B Piknova, WR Schief, V Vogel, BM Discher, SB Hall - Biophysical journal, 2001 - cell.com
The studies reported here used fluorescence microscopy and Brewster angle microscopy to
test the classical model of how pulmonary surfactant forms films that are metastable at high …