Cu-catalyzed azide− alkyne cycloaddition

M Meldal, CW Tornøe - Chemical reviews, 2008 - ACS Publications
The Huisgen 1, 3-dipolar cycloaddition reaction of organic azides and alkynes1, 2 has
gained considerable attention in recent years due to the introduction in 2001 of Cu (1) …

The copper (I)-catalyzed alkyne-azide cycloaddition (CuAAC)“click” reaction and its applications. An overview

L Liang, D Astruc - Coordination Chemistry Reviews, 2011 - Elsevier
A short overview of the copper (I)-catalyzed azide alkyne cycloaddition (CuAAC), the most
used “click” reaction, is presented, including the introduction of the “click” concept, the …

Ligand-accelerated Cu-catalyzed azide− alkyne cycloaddition: A mechanistic report

VO Rodionov, SI Presolski, D Díaz Díaz… - Journal of the …, 2007 - ACS Publications
The experimental rate law for the Cu (I)-catalyzed azide− alkyne cycloaddition (CuAAC)
reaction was found to vary in complex ways with concentration, the presence of chloride ion …

[HTML][HTML] Copper (I)-catalyzed cycloaddition of organic azides and 1-iodoalkynes

JE Hein, JC Tripp, LB Krasnova… - … (International ed. in …, 2009 - ncbi.nlm.nih.gov
The copper-catalyzed azide-alkyne cycloaddition reaction [1](CuAAC)(Scheme 1, a) is
known for its high fidelity in the presence of many functional groups and under demanding …

[引用][C] Mechanism of the Ligand‐Free CuI‐Catalyzed Azide–Alkyne Cycloaddition Reaction

VO Rodionov, VV Fokin, MG Finn - Angewandte Chemie, 2005 - Wiley Online Library
The 1, 3-dipolar cycloaddition of azides and alkynes [1] is an effective way to make
connections between structures that bear a wide variety of functional groups.[2] The process …

Advances of azide-alkyne cycloaddition-click chemistry over the recent decade

MS Singh, S Chowdhury, S Koley - Tetrahedron, 2016 - Elsevier
During the past years, a variety of scientific and methodological developments have been
achieved, which urge chemists to increase the tools of their arsenal to improve the ease and …

On the Mechanism of Copper (I)‐Catalyzed Azide–Alkyne Cycloaddition

L Zhu, CJ Brassard, X Zhang, PM Guha… - The Chemical …, 2016 - Wiley Online Library
The copper (I)‐catalyzed azide–alkyne cycloaddition (CuAAC) reaction regiospecifically
produces 1, 4‐disubstituted‐1, 2, 3‐triazole molecules. This heterocycle formation chemistry …

Chelation-assisted, copper (II)-acetate-accelerated azide− alkyne cycloaddition

GC Kuang, HA Michaels, JT Simmons… - The Journal of …, 2010 - ACS Publications
We described in a previous communication a variant of the popular CuI-catalyzed azide−
alkyne cycloaddition (AAC) process where 5 mol% of Cu (OAc) 2 in the absence of any …

Copper-catalysed azide–alkyne cycloadditions (CuAAC): an update

E Haldón, MC Nicasio, PJ Pérez - Organic & Biomolecular Chemistry, 2015 - pubs.rsc.org
The reactions of organic azides and alkynes catalysed by copper species represent the
prototypical examples of click chemistry. The so-called CuAAC reaction (copper-catalysed …

Benzimidazole and related ligands for Cu-catalyzed azide− alkyne cycloaddition

VO Rodionov, SI Presolski, S Gardinier… - Journal of the …, 2007 - ACS Publications
Tris (2-benzimidazolylmethyl) amines have been found to be superior accelerating ligands
for the copper (I)-catalyzed azide− alkyne cycloaddition reaction. Candidates bearing …