A mutualistic symbiosis between a parasitic mite and a pathogenic virus undermines honey bee immunity and health

G Di Prisco, D Annoscia, M Margiotta… - Proceedings of the …, 2016 - National Acad Sciences
Honey bee colony losses are triggered by interacting stress factors consistently associated
with high loads of parasites and/or pathogens. A wealth of biotic and abiotic stressors are …

[HTML][HTML] Synergistic parasite-pathogen interactions mediated by host immunity can drive the collapse of honeybee colonies

F Nazzi, SP Brown, D Annoscia, F Del Piccolo… - PLoS …, 2012 - journals.plos.org
The health of the honeybee and, indirectly, global crop production are threatened by several
biotic and abiotic factors, which play a poorly defined role in the induction of widespread …

Haemolymph removal by Varroa mite destabilizes the dynamical interaction between immune effectors and virus in bees, as predicted by Volterra's model

D Annoscia, SP Brown, G Di Prisco… - … of the Royal …, 2019 - royalsocietypublishing.org
The association between the deformed wing virus and the parasitic mite Varroa destructor
has been identified as a major cause of worldwide honeybee colony losses. The mite acts …

Superinfection exclusion and the long-term survival of honey bees in Varroa-infested colonies

GJ Mordecai, LE Brettell, SJ Martin, D Dixon… - The ISME …, 2016 - academic.oup.com
Over the past 50 years, many millions of European honey bee (Apis mellifera) colonies have
died as the ectoparasitic mite, Varroa destructor, has spread around the world. Subsequent …

Immunogene and viral transcript dynamics during parasitic Varroa destructor mite infection of developing honey bee (Apis mellifera) pupae

RD Kuster, HF Boncristiani… - Journal of Experimental …, 2014 - journals.biologists.com
The ectoparasitic Varroa destructor mite is a major contributor to the ongoing honey bee
health crisis. Varroa interacts with honey bee viruses, exacerbating their pathogenicity. In …

[HTML][HTML] Dynamic evolution in the key honey bee pathogen deformed wing virus: Novel insights into virulence and competition using reverse genetics

EV Ryabov, AK Childers, D Lopez, K Grubbs… - PLoS …, 2019 - journals.plos.org
The impacts of invertebrate RNA virus population dynamics on virulence and infection
outcomes are poorly understood. Deformed wing virus (DWV), the main viral pathogen of …

Impact of an ectoparasite on the immunity and pathology of an invertebrate: evidence for host immunosuppression and viral amplification

X Yang, DL Cox-Foster - Proceedings of the National …, 2005 - National Acad Sciences
Varroa mites (Varroa destructor) are ectoparasites of honey bees (Apis mellifera) and cause
serious damage to bee colonies. The mechanism of how varroa mites kill honey bees …

Evidence for damage-dependent hygienic behaviour towards Varroa destructor-parasitised brood in the western honey bee, Apis mellifera

C Schöning, S Gisder, S Geiselhardt… - Journal of …, 2012 - journals.biologists.com
The ectoparasitic mite Varroa destructor and honey bee pathogenic viruses have been
implicated in the recent demise of honey bee colonies. Several studies have shown that the …

[HTML][HTML] Pupal cannibalism by worker honey bees contributes to the spread of deformed wing virus

F Posada-Florez, ZS Lamas, DJ Hawthorne, Y Chen… - Scientific Reports, 2021 - nature.com
Transmission routes impact pathogen virulence and genetics, therefore comprehensive
knowledge of these routes and their contribution to pathogen circulation is essential for …

[HTML][HTML] Absence of deformed wing virus and Varroa destructor in Australia provides unique perspectives on honeybee viral landscapes and colony losses

JMK Roberts, DL Anderson, PA Durr - Scientific reports, 2017 - nature.com
Honeybee (Apis mellifera) health is threatened globally by the complex interaction of
multiple stressors, including the parasitic mite Varroa destructor and a number of pathogenic …