Metabolic phenotypes in asthmatic adults: Relationship with inflammatory and clinical phenotypes and prognostic implications

A Santos, H Pité, C Chaves-Loureiro, SM Rocha… - Metabolites, 2021 - mdpi.com
Bronchial asthma is a chronic disease that affects individuals of all ages. It has a high
prevalence and is associated with high morbidity and considerable levels of mortality …

Metabolomics in the Identification of Biomarkers of Asthma

A Villaseñor, I Eguiluz-Gracia, A Moreira, CE Wheelock… - Metabolites, 2021 - mdpi.com
Asthma is a major non-communicable disease characterized by recurrent attacks of
breathlessness and wheezing. According to World Health Organization (WHO), it is …

Urinary metabolomic profiling of asthmatics can be related to clinical characteristics

CC Loureiro, AS Oliveira, M Santos, A Rudnitskaya… - Allergy, 2016 - Wiley Online Library
Metabolomics has been increasingly explored to achieve an improved understanding of
asthma. In the current observational and exploratory study, the first to have examined the …

Potential metabolic biomarkers in adult asthmatics

S Sim, Y Choi, HS Park - Metabolites, 2021 - mdpi.com
Asthma is the most common chronic airway inflammation, with multiple phenotypes caused
by complicated interactions of genetic, epigenetic, and environmental factors. To date …

Metabolomics in asthma

BA Luxon - Heterogeneity in Asthma, 2013 - Springer
Asthma and airway inflammation are responses to infectious stimuli and the mechanisms of
how they are mediated, whether by the innate or adaptive immune response systems, are …

Asthma metabolomics and the potential for integrative omics in research and the clinic

RS Kelly, A Dahlin, MJ McGeachie, W Qiu, J Sordillo… - Chest, 2017 - Elsevier
Asthma is a complex disease well-suited to metabolomic profiling, both for the development
of novel biomarkers and for the improved understanding of pathophysiology. In this review …

Metabolic interactions in asthma

M Farraia, J Cavaleiro Rufo… - Eur Ann Allergy …, 2019 - repositorio-aberto.up.pt
Metabolomics can be used to explore altered metabolic pathways in asthma, giving insights
into its pathophysiology. We aimed to review how metabolomics has been used to …

Metabolic Contributions to Pathobiology of Asthma

T Roshan Lal, LR Cechinel, R Freishtat, D Rastogi - Metabolites, 2023 - mdpi.com
Asthma is a heterogenous disorder driven by inflammatory mechanisms that result in
multiple phenotypes. Given the complex nature of this condition, metabolomics is being …

Metabolomic profiling differences among asthma, COPD, and healthy subjects: a LC-MS-based metabolomic analysis

Y Liang, XY Gai, C Chang, X Zhang, W Juan… - Biomedical and …, 2019 - Elsevier
Objective Asthma and chronic obstructive pulmonary disease (COPD) feature different
inflammatory and cellular profiles in the airways, indicating that the cellular metabolic …

Serum metabolomics analysis of asthma in different inflammatory phenotypes: a cross‐sectional study in Northeast China

Z Pang, G Wang, C Wang, W Zhang… - BioMed Research …, 2018 - Wiley Online Library
Background and Objective. Asthma as a chronic heterogeneous disease seriously affects
the quality of life. Incorrect identification for its clinical phenotypes lead to a huge waste of …