Cytokines in inflammatory disease

S Kany, JT Vollrath, B Relja - International journal of molecular sciences, 2019 - mdpi.com
This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines.
Numerous studies have implicated that inflammatory cytokines exert important effects with …

IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases

X Song, Y Qian - Cellular signalling, 2013 - Elsevier
Inflammation is the immediate protective response of the body to pathogen invasions,
allergen challenges, chemical exposures or physical injuries. Acute inflammation usually …

Recent advances in the biology of IL-1 family cytokines and their potential roles in development of sepsis

Y Ge, M Huang, Y Yao - Cytokine & Growth Factor Reviews, 2019 - Elsevier
The IL-1 family comprises two anti-inflammatory cytokines (IL-37, IL-38), two receptor
antagonists (IL-1ra, IL-36ra), and seven ligand agonists (IL-1α, IL-1β, IL-33, IL-36α, IL-36β …

IL-6 in inflammation, autoimmunity and cancer

T Hirano - International immunology, 2021 - academic.oup.com
IL-6 is involved both in immune responses and in inflammation, hematopoiesis, bone
metabolism and embryonic development. IL-6 plays roles in chronic inflammation (closely …

[HTML][HTML] The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions

V Carlini, DM Noonan, E Abdalalem, D Goletti… - Frontiers in …, 2023 - frontiersin.org
Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating
inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory …

IL-33/IL-31 axis in immune-mediated and allergic diseases

G Murdaca, M Greco, A Tonacci, S Negrini… - International journal of …, 2019 - mdpi.com
Several allergic and immunologic diseases including asthma, food allergy (FA), chronic
spontaneous urticaria (CSU), atopic dermatitis (AD), systemic lupus erythematosus (SLE) …

IL‐33/IL‐31 Axis: a potential inflammatory pathway

E Di Salvo, E Ventura-Spagnolo… - Mediators of …, 2018 - Wiley Online Library
Cytokines play an important role in the regulation of the immune system (adaptive and
innate). Given their importance in proinflammatory processes, cytokines have been used for …

Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons?

H Mühl - Frontiers in immunology, 2013 - frontiersin.org
Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share
characteristic properties such as defined structural features, usage of IL-10R2 as one …

The IL-1 family of cytokines and receptors in rheumatic diseases

CA Dinarello - Nature Reviews Rheumatology, 2019 - nature.com
More than any other cytokine family, the 11 members of the IL-1 family are associated with
innate immune responses, which occur in acute inflammation and chronic inflammatory …

Regulation and functions of the IL-10 family of cytokines in inflammation and disease

W Ouyang, S Rutz, NK Crellin, PA Valdez… - Annual review of …, 2011 - annualreviews.org
The IL-10 family of cytokines consists of nine members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-
26, and the more distantly related IL-28A, IL-28B, and IL-29. Evolutionarily, IL-10 family …