Neuroinflammation, characterized by the activation of glial cells, is a hallmark in several
neurological and neurodegenerative disorders. Inadequate inflammation cannot eliminate …

In an ageing society, neurodegenerative diseases have attracted attention because of their
high incidence worldwide. Despite extensive research, there is a lack of conclusive insights …

Recent literature has pointed to the existence of inflammasome-mediated inflammatory
pathways in central nervous system (CNS) disorders and associated changes in behavior …

Neurodegenerative diseases are chronic, progressive disorders that occur in the central
nervous system (CNS). They are characterized by the loss of neuronal structure and function …

The prevalence of neurodegenerative disease has increased significantly in recent years,
and with a rapidly aging global population, this trend is expected to continue. These …

Neurodegenerative diseases are neuronal disorders characterized by the loss of a large
number of neurons in the human brain. Innate immunity-mediated neuroinflammation …

Neuroinflammation is becoming increasingly recognized as a critical factor in the pathology
of both acute and chronic neurological conditions. Inflammasomes such as the one formed …

Neuroinflammatory response is the immune response mechanism of the innate immune
system of the central nervous system. Both primary and secondary injury can activate …

Neurodegenerative diseases are characterized by a dysregulated neuro-glial
microenvironment, culminating in functional deficits resulting from neuronal cell death …

The NLRP inflammasome is a multi-protein complex which mainly consists of the nucleotide-
binding oligomerization domain, leucine-rich repeat, and pyrin domain. Its activation is …