[HTML][HTML] A critical role for plasminogen in inflammation

SK Baker, S Strickland - Journal of Experimental Medicine, 2020 - rupress.org
Plasminogen and its active form, plasmin, have diverse functions related to the inflammatory
response in mammals. Due to these roles in inflammation, plasminogen has been …

Plasmin as a proinflammatory cell activator

T Syrovets, O Lunov, T Simmet - Journal of leukocyte biology, 2012 - academic.oup.com
Review of the available evidence for physiological and pathophysiological roles of the
serine protease plasmin in inflammatory processes. The serine protease plasmin generated …

[HTML][HTML] The multifaceted role of plasminogen in inflammation

B Heissig, Y Salama, S Takahashi, T Osada, K Hattori - Cellular signalling, 2020 - Elsevier
A fine-tuned activation and deactivation of proteases and their inhibitors are involved in the
execution of the inflammatory response. The zymogen/proenzyme plasminogen is converted …

Plasmin: a modulator of immune function

DF Draxler, M Sashindranath… - Seminars in thrombosis …, 2017 - thieme-connect.com
Plasmin is the effector protease of the fibrinolytic system, well known for its involvement in
fibrin degradation and clot removal. However, plasmin is also recognized as a potent …

Plasminogen is a critical regulator of cutaneous wound healing

R Sulniute, Y Shen, YZ Guo, M Fallah… - Thrombosis and …, 2016 - thieme-connect.com
Wound healing is a complicated biological process that consist of partially overlapping
inflammatory, proliferation and tissue remodelling phases. A successful wound healing …

The functions of plasminogen in cardiovascular disease

EF Plow, J Hoover-Plow - Trends in cardiovascular medicine, 2004 - Elsevier
Plasminogen (Plg) and its derivative serine protease, plasmin, together with the activators,
inhibitors, modulators, and substrates of the Plg network, are postulated to regulate a wide …

Plasmin (ogen) at the nexus of fibrinolysis, inflammation, and complement

JH Foley - Seminars in thrombosis and hemostasis, 2017 - thieme-connect.com
The diverse mechanisms by which the plasmin (ogen) system is involved in human
physiology and pathology are constantly being delineated. For many years, the plasmin …

Plasminogen deficiency differentially affects recruitment of inflammatory cell populations in mice

VA Ploplis, EL French, P Carmeliet… - Blood, The Journal …, 1998 - ashpublications.org
It is widely held that the plasminogen (Plg) system plays a role in inflammation through
plasmin-mediated directional cell migration. However, substantial evidence for its …

Structure and function of the plasminogen/plasmin system

FJ Castellino, VA Ploplis - Thrombosis and haemostasis, 2005 - thieme-connect.com
Activation of the fibrinolytic system is dependent on the conversion of the plasma zymogen,
plasminogen (Pg), to the serine protease plasmin (Pm) by the physiological activators …

Novel aspects and new roles for the serine protease plasmin

T Syrovets, T Simmet - Cellular and Molecular Life Sciences CMLS, 2004 - Springer
The serine protease plasmin is distributed throughout the human body in the form of the
zymogen plasminogen. The plasminogen activation system is mostly recognized for its …