Vitamin D deficiency, characterized by low circulating levels of calcifediol (25-
hydroxyvitamin D, 25D) has been linked to increased risk of infections of bacterial and viral …

Vitamin D, best known for its role in skeletal health, has emerged as a key regulator of innate
immune responses to microbial threat. In immune cells such as macrophages, expression of …

While many global mechanisms of innate immune responses to pathogen threat are
conserved over a vast range of species, the details of those responses and their regulation …

Vitamin D has emerged as a pleiotropic regulator of human physiology, and recent work has
revealed that it has several roles in control of human immune system function. Vitamin D …

Vitamin D deficiency has been correlated with increased rates of infection. Since the early
19th century, both environmental (ie, sunlight) and dietary sources (cod liver) of vitamin D …

The hormonal form of vitamin D 3, 1, 25-dihydroxyvitamin D 3 (1, 25 (OH) 2 D 3), is an
immune system modulator and induces expression of the TLR coreceptor CD14. 1, 25 (OH) …

Vitamin D was first identified as a cure for nutritional rickets, a disease of bone growth
caused by an inadequate uptake of dietary calcium. It is now known that vitamin D can be …

Vitamin D was discovered as the preventive agent of nutritional rickets, a defect in bone
development due to inadequate uptake of dietary calcium. However, a variety of studies over …

An immunomodulatory role for vitamin D was first proposed more than 25 years ago, based
on two salient observations. Firstly it was shown that monocytes/macrophages from patients …

Purpose Vitamin D is increasingly thought to play a role in regulating immunity. This
comprehensive review updates the current understanding regarding ways in which we …