Cryptococcal-related mortality despite fluconazole preemptive treatment in a cryptococcal antigen screen-and-treat program

RM Wake, NP Govender, T Omar, C Nel… - Clinical Infectious …, 2020 - academic.oup.com
Abstract Background Cryptococcal antigen (CrAg) screening and treatment with preemptive
fluconazole reduces the incidence of clinically evident cryptococcal meningitis in individuals …

[HTML][HTML] Serum cryptococcal antigen (CRAG) screening is a cost-effective method to prevent death in HIV-infected persons with CD4≤ 100/μL starting HIV therapy in …

DB Meya, YC Manabe, B Castelnuovo… - … diseases: an official …, 2010 - ncbi.nlm.nih.gov
Background Cryptococcal meningitis (CM) remains a common AIDS-defining illness in Africa
and Asia. Sub-clinical cryptococcal antigenemia is frequently unmasked with antiretroviral …

Cost-Effectiveness of Serum Cryptococcal Antigen Screening to Prevent Deaths among HIV-Infected Persons with a CD4+ Cell Count ≤100 Cells/μL Who Start HIV …

DB Meya, YC Manabe, B Castelnuovo… - Clinical infectious …, 2010 - academic.oup.com
Background. Cryptococcal meningitis (CM) remains a common AIDS-defining illness in
Africa and Asia. Subclinical cryptococcal antigenemia is frequently unmasked with …

[HTML][HTML] Cryptococcal antigenemia is associated with meningitis or death in HIV-infected adults with CD4 100–200 cells/mm3

J Wykowski, SR Galagan, S Govere, CL Wallis… - BMC Infectious …, 2020 - Springer
Abstract Background Cryptococcal antigen (CrAg) screening with fluconazole prophylaxis
has been shown to prevent cryptococcal meningitis and mortality for people living with HIV …

[HTML][HTML] Reflexive laboratory-based cryptococcal antigen screening and preemptive fluconazole therapy for cryptococcal antigenemia in HIV-infected individuals with …

DB Meya, AN Kiragga, E Nalintya… - JAIDS Journal of …, 2019 - journals.lww.com
Background: HIV-infected persons with cryptococcal antigenemia (CrAg) are at high risk for
meningitis or death. We evaluated the effect of CrAg screening and preemptive fluconazole …

High cryptococcal antigen titers in blood are predictive of subclinical cryptococcal meningitis among human immunodeficiency virus-infected patients

RM Wake, E Britz, C Sriruttan, I Rukasha… - Clinical infectious …, 2018 - academic.oup.com
Background High mortality rates among asymptomatic cryptococcal antigen (CrAg)–positive
patients identified through CrAg screening, despite preemptive fluconazole treatment, may …

Impact of prior cryptococcal antigen screening on in-hospital mortality in cryptococcal meningitis or fungaemia among HIV-seropositive individuals in South Africa: a …

O Paccoud, L Shuping, R Mashau, G Greene… - Clinical Microbiology …, 2023 - Elsevier
Objectives We investigated whether patients with cryptococcal meningitis (CM) or fungaemia
detected through South Africa's laboratory cryptococcal antigen (CrAg) screening …

Impact of routine cryptococcal antigen screening and targeted preemptive fluconazole therapy in antiretroviral-naive human immunodeficiency virus–infected adults …

E Temfack, JJ Bigna, HN Luma, R Spijker… - Clinical Infectious …, 2019 - academic.oup.com
Cryptococcal antigen (CrAg) screening and targeted preemptive fluconazole in antiretroviral-
naive human immunodeficiency virus–infected adults with CD4 cell counts< 100/μL seems …

Outpatient cryptococcal antigen screening is associated with favorable baseline characteristics and improved survival in persons with cryptococcal meningitis in …

AE Levin, AS Bangdiwala, E Nalintya… - Clinical Infectious …, 2023 - academic.oup.com
Background It is unknown whether persons with symptomatic cryptococcal meningitis
detected during routine blood cryptococcal antigen (CrAg) screening have better survival …

[HTML][HTML] Universal screening of Tanzanian HIV-infected adult inpatients with the serum cryptococcal antigen to improve diagnosis and reduce mortality: an operational …

BMK Wajanga, S Kalluvya, JA Downs… - Journal of the …, 2011 - Springer
Background Cryptococcal meningitis is a leading cause of death among HIV-infected
individuals in sub-Saharan Africa. Recent developments include the availability of …