[HTML][HTML] Respiratory syncytial virus vaccines: a review of the candidates and the approved vaccines

X Topalidou, AM Kalergis, G Papazisis - Pathogens, 2023 - mdpi.com
Respiratory syncytial virus (RSV) is responsible for a significant proportion of global
morbidity and mortality affecting young children and older adults. In the aftermath of formalin …

[HTML][HTML] Current state and challenges in developing respiratory syncytial virus vaccines

C Biagi, A Dondi, S Scarpini, A Rocca, S Vandini… - Vaccines, 2020 - mdpi.com
Respiratory syncytial virus (RSV) is the main cause of acute respiratory tract infections in
infants and it also induces significant disease in the elderly. The clinical course may be …

Vaccines against human respiratory syncytial virus in clinical trials, where are we now?

I Rossey, X Saelens - Expert review of vaccines, 2019 - Taylor & Francis
Introduction: Human respiratory syncytial virus (RSV) is a major health threat both for the
very young and the elderly. With yearly 3.2 million hospital admissions and approximately …

[HTML][HTML] Strategic priorities for respiratory syncytial virus (RSV) vaccine development

LJ Anderson, PR Dormitzer, DJ Nokes, R Rappuoli… - Vaccine, 2013 - Elsevier
Although RSV has been a high priority for vaccine development, efforts to develop a safe
and effective vaccine have yet to lead to a licensed product. Clinical and epidemiologic …

Respiratory syncytial virus vaccine: a systematic overview with emphasis on respiratory syncytial virus subunit vaccines

EAF Simoes, DHS Tan, A Ohlsson, V Sales, EEL Wang - Vaccine, 2001 - Elsevier
Objective: To explore whether RSV vaccines are efficacious in preventing respiratory
syncytial virus (RSV) lower respiratory infection (LRI). Methods: Randomized clinical trials …

The journey to a respiratory syncytial virus vaccine

A Mejias, R Rodríguez-Fernández, S Oliva… - Annals of Allergy …, 2020 - Elsevier
Objective The high burden associated with respiratory syncytial virus (RSV) has made the
development of RSV vaccine (s) a global health high priority. This review summarizes the …

[HTML][HTML] WHO consultation on respiratory syncytial virus vaccine development report from a World Health Organization meeting held on 23–24 March 2015

K Modjarrad, B Giersing, DC Kaslow, PG Smith… - Vaccine, 2016 - Elsevier
Respiratory syncytial virus (RSV) is a globally prevalent cause of lower respiratory infection
in neonates and infants. Despite its disease burden, a safe and effective RSV vaccine has …

Respiratory syncytial virus vaccine development

JL Hurwitz - Expert review of vaccines, 2011 - Taylor & Francis
Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract viral disease
in infants and young children. Presently, there are no explicit recommendations for RSV …

Priorities for developing respiratory syncytial virus vaccines in different target populations

SB Drysdale, RS Barr, CS Rollier, CA Green… - Science translational …, 2020 - science.org
The development of an effective vaccine against respiratory syncytial virus (RSV) has been
hampered by major difficulties that occurred in the 1960s when a formalin-inactivated …

Current concepts and progress in RSV vaccine development

AK Guvenel, C Chiu, PJM Openshaw - Expert review of vaccines, 2014 - Taylor & Francis
Respiratory syncytial virus (RSV) disease is an important cause of morbidity and mortality in
children and debilitated adults and remains one of the major global unmet challenges for …