Non-small cell lung cancer (NSCLC) is among the leading global causes of cancer-related
mortality. Current treatment options have limited efficacy and severe adverse effects …

Nuclear factor κB (NFκB) is a unique protein complex that plays a major role in lung
inflammation and respiratory dysfunction. The NFκB signaling pathway, therefore becomes …

As a prototypical pro-inflammatory transcription factor, constitutive activation of NF-κB
signaling pathway has been reported in several chronic inflammatory disorders including …

Chronic respiratory diseases like asthma and Chronic Obstructive Pulmonary Disease
(COPD) have been a burden to society for an extended period. Currently, there are only …

The transcription factor nuclear factor-κB (NF-κB) is a critical regulator of the immune
response, inflammation, cell growth, and survival. Canonical and non-canonical pathways …

The decoy oligodeoxynucleotide (ODN) serves as a decoy sequence for a target
transcription factor, then inhibiting its binding to the authentic sequence at the promoter, and …

Background: Nuclear factor-kappaB (NF-κB), a transcription factor, is abundantly expressed
in many tumorsand regulates many tumor-relative genes such as c-myc and caspase-8 …

The objectives of this study were to investigate a nuclear factor-kappa B (NFκB) decoy
oligonucleotide (ODN) strategy on the inhibition of glioblastoma (GBM) cell line growth and …

In the last two decades, frontiers in new drug development are represented by genetic code
inhibitors. Nuclear factor-κB (NF-κB) is a transcription factor playing critical roles in many …

The objective of this study was to evaluate a poly (dl-lactic-co-glycolic acid)/poly (ethylene
glycol)(PLGA/PEG) delivery system for nuclear factor-kappa B (NFκB) decoy …