The Staphylococcus aureus genome encodes three ferric uptake regulator (Fur)
homologues: Fur, PerR, and Zur. To determine the exact role of PerR, we inactivated the …

The Staphylococcus aureus genome encodes three ferric uptake repressor (Fur)
homologues: Fur, PerR, and Zur. To determine the exact role of Fur in S. aureus, we …

Iron is an essential nutrient for the survival and pathogenesis of bacteria, but relatively little
is known regarding its transport and regulation in staphylococci. Based on the known …

Ferric uptake regulator (Fur) and Fur-like proteins form an important family of transcriptional
regulators in many bacterial species. In this work we have characterized a Fur-like protein …

Summary The Staphylococcus aureus DtxR‐like protein, MntR, controls expression of the
mntABC and mntH genes, which encode putative manganese transporters. Mutation of …

Staphylococcus aureus can proliferate in iron-limited environments such as the mammalian
host. The transcriptional profiles of 460 genes (iron-regulated, putative Fur-regulated …

The tremendous success of Staphylococcus aureus as a pathogen is due to the controlled
expression of a diverse array of virulence factors. The effects of host environments on the …

The unique redox potential of iron makes it an ideal cofactor in diverse biochemical
reactions. Iron is therefore vital for the growth and proliferation of nearly all organisms …

The acquisition of iron by pathogenic bacteria is often a crucial step in establishing infection.
To accomplish this, many bacteria, including Staphylococcus aureus, produce low …

Oxidative-stress resistance in Staphylococcus aureus is linked to metal ion homeostasis via
several interacting regulators. In particular, PerR controls the expression of a regulon of …