Fungal infections are increasing globally, causing alarmingly high mortality and economic
burden. In addition to antifungal resistance, other more subtle drug responses appear to …

Systemic fungal infections pose a serious clinical problem. Treatment options are limited,
and antifungal drug resistance is increasing. In addition, a substantial proportion of patients …

Highlights•Our limited arsenal of antifungals is threatened by drug-resistant fungal
pathogens.•Inherent resistance is when all strains of a species show antifungal …

Invasive fungal infections remain a major source of global morbidity and mortality, especially
among patients with underlying immune suppression. Successful patient management …

Fungal pathogens cause life-threatening infections in immunocompetent and
immunocompromised individuals. Millions of people die each year due to fungal infections …

Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …

in brief Page 1 in brief nature reviews | Microbiology 0123456789();: MICROBIOME Gut
commensals activate digestion Gut bacteria are important for digestion in animals but further study …

Antifungal therapy is a central component of patient management for acute and chronic
mycoses. Yet, treatment choices are restricted because of the sparse number of antifungal …

A restricted number of antifungal agents are available for the therapy of fungal diseases.
With the introduction of epidemiological cut-off values for each agent in important fungal …

Antifungal resistance is a growing concern as it poses a significant threat to public health.
Fungal infections are a significant cause of morbidity and mortality, especially in …