Background Accumulation of amyloid beta, tau hyperphosphorylation, and microglia
activation are the three highly acknowledged pathological factors of Alzheimer's disease …

Considerable evidence has shown that the breakdown of myelin has been linked to
Alzheimer's disease (AD). Considering the vulnerability of oligodendrocytes to Alzheimer's …

Alzheimer's disease (AD) is an age-related neurodegenerative disease seriously influencing
the quality of life and is a global health problem. Many factors affect the onset and …

In Alzheimer's disease (AD), amyloid-β (Aβ) is thought to be of neuronal origin. However, in
single-cell RNAseq datasets from mouse and human, we found transcripts of amyloid …

Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in
humans, but still no curative treatment has been developed. Although many explicative …

Oligodendrocytes form the myelin that ensheaths CNS axons, which is essential for rapid
neuronal signalling and underpins the massive computing power of the human brain …

Astrocytes are involved in various processes in the central nervous system (CNS). As the
most abundant cell type in the CNS, astrocytes play an essential role in neuronal …

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease worldwide. With
the increasing trend of population aging, the estimated number of AD continues to climb …

Extensive evidence has indicated that the breakdown of myelin is associated with
Alzheimer's disease (AD) since the vulnerability of oligodendrocytes under Alzheimer's …

Alzheimer's disease (AD) is the most common neurodegenerative disease and the most
common cause of dementia. Among various pathophysiological aspects, microglia are …