[HTML][HTML] Waves, patterns, bifurcations: A tutorial review on the vertebrate segmentation clock
P François, V Mochulska - Physics Reports, 2024 - Elsevier
Proper vertebrae formation relies on a tissue-wide oscillator called the segmentation clock.
Individual cellular oscillators in the presomitic mesoderm are modulated by intercellular …
Individual cellular oscillators in the presomitic mesoderm are modulated by intercellular …
Patterning embryos with oscillations: structure, function and dynamics of the vertebrate segmentation clock
The segmentation clock is an oscillating genetic network thought to govern the rhythmic and
sequential subdivision of the elongating body axis of the vertebrate embryo into somites: the …
sequential subdivision of the elongating body axis of the vertebrate embryo into somites: the …
Delayed coupling theory of vertebrate segmentation
Rhythmic and sequential subdivision of the elongating vertebrate embryonic body axis into
morphological somites is controlled by an oscillating multicellular genetic network termed …
morphological somites is controlled by an oscillating multicellular genetic network termed …
Cell-autonomous timing drives the vertebrate segmentation clock's wave pattern
LA Rohde, A Bercowsky-Rama, G Valentin… - bioRxiv, 2021 - biorxiv.org
Rhythmic and sequential segmentation of the growing vertebrate body relies on the
segmentation clock, a multi-cellular oscillating genetic network. The clock is visible as tissue …
segmentation clock, a multi-cellular oscillating genetic network. The clock is visible as tissue …
[HTML][HTML] From signalling oscillations to somite formation
WHM Meijer, KF Sonnen - Current Opinion in Systems Biology, 2024 - Elsevier
Periodic segmentation of vertebrate embryos or somitogenesis is regulated by a dynamic
network of signalling pathways. Signalling gradients determine the spacing of the forming …
network of signalling pathways. Signalling gradients determine the spacing of the forming …
In vitro systems: A new window to the segmentation clock
M Diaz‐Cuadros, O Pourquie - Development, Growth & …, 2021 - Wiley Online Library
Segmental organization of the vertebrate body plan is established by the segmentation
clock, a molecular oscillator that controls the periodicity of somite formation. Given the …
clock, a molecular oscillator that controls the periodicity of somite formation. Given the …
[HTML][HTML] Waiting on the Fringe: cell autonomy and signaling delays in segmentation clocks
AC Oates - Current Opinion in Genetics & Development, 2020 - Elsevier
The rhythmic and sequential segmentation of the vertebrate body axis into somites during
embryogenesis is governed by a multicellular, oscillatory patterning system called the …
embryogenesis is governed by a multicellular, oscillatory patterning system called the …
A mechanical perspective on vertebral segmentation
Segmentation is a characteristic feature of the vertebrate body plan. The prevailing
paradigm explaining its origin is the 'clock and wave-front'model, which assumes that the …
paradigm explaining its origin is the 'clock and wave-front'model, which assumes that the …
Cell cycle regulation of oscillations yields coupling of growth and form in a computational model of the presomitic mesoderm
PJ Murray, FA Carrieri, JK Dale - Journal of Theoretical Biology, 2019 - Elsevier
A striking example of coupling between growth and form occurs during the segmentation of
the vertebrate embryo. During segmentation, pairs of segments, one on either side of the …
the vertebrate embryo. During segmentation, pairs of segments, one on either side of the …
[HTML][HTML] Segmentation clock dynamics is strongly synchronized in the forming somite
R Bhavna - Developmental biology, 2020 - Elsevier
During vertebrate somitogenesis an inherent segmentation clock coordinates the
spatiotemporal signaling to generate segmented structures that pattern the body axis. Using …
spatiotemporal signaling to generate segmented structures that pattern the body axis. Using …