Capsaicin‐induced vasodilatation of human coronary arteries in vitro is mediated by calcitonin gene‐related peptide rather than substance P or neurokinin A

A Franco‐Cereceda, A Rudehill - Acta physiologica …, 1989 - Wiley Online Library
In the present study the possible influence of capsaicin on human arterial coronary tone in
vitro was studied in relation to the vasodilatory properties of calcitonin gene‐related peptide …

Calcitonin gene-related peptide but not substance P mimics capsaicin-induced coronary vasodilation in the pig

A Franco-Cereceda, A Rudehill… - European journal of …, 1987 - Elsevier
The vasodilator effects of the human calcitonin gene-related peptides α (hCGRPα) and β
(hCGRPβ) were studied in vitro and in vivo in relation to the effects of substance P (SP) and …

Heterogeneous involvement of endothelium in calcitonin gene-related peptide-induced relaxation in coronary arteries from rat.

D Prieto, S Benedito, NC Nyborg - British journal of pharmacology, 1991 - ncbi.nlm.nih.gov
The effects of rat-and human-CGRP and capsaicin were studied in isolated rings of rat
proximal epicardial (PC) and distal intramyocardial (DC) coronary arteries. 2. The relaxing …

Calcitonin gene-related peptide and tachykinins in relation to local sensory control of cardiac contractility and coronary vascular tone.

A Franco-Cereceda - Acta physiologica Scandinavica …, 1988 - europepmc.org
The possible role of peptides locally released from sensory nerves in the control of cardiac
contractility and the coronary vascular tone was investigated in the present study …

Calcitonin gene‐related peptide and human epicardial coronary arteries: presence, release and vasodilator effects

A Franco‐Cereceda - British journal of pharmacology, 1991 - Wiley Online Library
1 In the present study, the levels of calcitonin gene‐related peptide (CGRP)‐like
immunoreactivity (‐LI) in human cardiopulmonary tissue were determined in combination …

Effects of substance P, calcitonin gene-related peptide and capsaicin on tension and membrane potential of pig coronary artery in vitro

JL Bény, PC Brunet, H Huggel - Regulatory peptides, 1989 - Elsevier
The effects of substance P (SP), calcitonin gene-related peptide (CGRP) and capsaicin were
studied on isometric tension and membrane potential of pig coronary arterial strips in vitro …

Pharmacological characterisation of capsaicin-induced relaxations in human and porcine isolated arteries

S Gupta, J Lozano-Cuenca, CM Villalón… - Naunyn-Schmiedeberg's …, 2007 - Springer
Capsaicin, a pungent constituent from red chilli peppers, activates sensory nerve fibres via
transient receptor potential vanilloid receptors type 1 (TRPV1) to release neuropeptides like …

Role of nitric oxide in the dilator actions of capsaicin-sensitive nerves in the rabbit coronary circulation

JA Mitchell, FM Williams, TJ Williams, SW Larkin - Neuropeptides, 1997 - Elsevier
Perivascular sensory nerves release calcitonin gene-related peptide (CGRP) and substance
P, the dilator actions of which can be regulated by nitric oxide (NO). This study investigated …

Calcitonin gene-related peptide (CGRP) and capsaicin-induced stimulation of heart contractile rate and force

A Franco-Cereceda, JM Lundberg - Naunyn-Schmiedeberg's archives of …, 1985 - Springer
The effects of calcitonin gene-related peptide (CGRP) on guinea-pig heart contractility were
investigated in vitro in relation to the responce of capsaicin and noradrenaline (NA). 2 …

A comparison of bradykinin‐and capsaicin‐induced myocardial and coronary effects in isolated perfused heart of guinea‐pig: involvement of substance P and …

S Manzini, F Perretti, L de Benedetti… - British journal of …, 1989 - Wiley Online Library
1 Bradykinin and capsaicin were compared for their ability to elicit functional effects and to
release sensory neuropeptides from guinea‐pig isolated perfused hearts. 2 Both bradykinin …