Lung cancer is the most common form of cancer death worldwide. Although reduction of
tobacco consumption remains the most appropriate strategy to reduce lung-cancer burden …

Lung cancer is a leading cause of cancer death and disease burden in many countries.
Understanding of the biological pathways involved in lung cancer aetiology is required to …

CHEK2 is a key cell cycle control gene encoding a pluripotent kinase that can cause arrest
or apoptosis in response to unrepaired DNA damage. We report a large case-control study …

Recent genome-wide association studies (GWASs) have identified common genetic variants
at 5p15. 33, 6p21–6p22 and 15q25. 1 associated with lung cancer risk. Several other …

Lung cancer is a major cause of cancer-related mortality in the USA, and tobacco smoke is
the major risk factor for this disease. However, many patients with lung cancer have never …

We conducted imputation to the 1000 Genomes Project of four genome-wide association
studies of lung cancer in populations of European ancestry (11,348 cases and 15,861 …

Background Lung cancer in individuals who have never smoked tobacco products is an
increasing medical and public-health issue. We aimed to unravel the genetic basis of lung …

Lung cancer is one of the most common and deadliest cancers in the world. The major socio-
environmental risk factor involved in the development of lung cancer is cigarette smoking …

Lung cancer is the leading cause of cancer death worldwide, and cigarette smoking is the
major environmental factor for its development. To elucidate the genetic differences in the …

Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …