Bacteriophage resistance mechanisms

SJ Labrie, JE Samson, S Moineau - Nature Reviews Microbiology, 2010 - nature.com
Phages are now acknowledged as the most abundant microorganisms on the planet and
are also possibly the most diversified. This diversity is mostly driven by their dynamic …

Bacteriophage strategies for overcoming host antiviral immunity

Z Gao, Y Feng - Frontiers in Microbiology, 2023 - frontiersin.org
Phages and their bacterial hosts together constitute a vast and diverse ecosystem. Facing
the infection of phages, prokaryotes have evolved a wide range of antiviral mechanisms …

The phage‐host arms race: shaping the evolution of microbes

A Stern, R Sorek - Bioessays, 2011 - Wiley Online Library
Bacteria, the most abundant organisms on the planet, are outnumbered by a factor of 10 to 1
by phages that infect them. Faced with the rapid evolution and turnover of phage particles …

The highly diverse antiphage defence systems of bacteria

H Georjon, A Bernheim - Nature Reviews Microbiology, 2023 - nature.com
Bacteria and their viruses have coevolved for billions of years. This ancient and still ongoing
arms race has led bacteria to develop a vast antiphage arsenal. The development of high …

Bacteriophage-host arm race: an update on the mechanism of phage resistance in bacteria and revenge of the phage with the perspective for phage therapy

AH Azam, Y Tanji - Applied microbiology and biotechnology, 2019 - Springer
Due to a constant attack by phage, bacteria in the environment have evolved diverse
mechanisms to defend themselves. Several reviews on phage resistance mechanisms have …

Fitness trade-offs resulting from bacteriophage resistance potentiate synergistic antibacterial strategies

MR Mangalea, BA Duerkop - Infection and immunity, 2020 - Am Soc Microbiol
Bacteria that cause life-threatening infections in humans are becoming increasingly difficult
to treat. In some instances, this is due to intrinsic and acquired antibiotic resistance …

Virulence reduction in bacteriophage resistant bacteria

M León, R Bastías - Frontiers in microbiology, 2015 - frontiersin.org
Bacteriophages can influence the abundance, diversity, and evolution of bacterial
communities. Several bacteriophages have been reported to add virulence factors to their …

[HTML][HTML] Beyond antibacterials–exploring bacteriophages as antivirulence agents

Y Shen, MJ Loessner - Current Opinion in Biotechnology, 2021 - Elsevier
Highlights•Surface receptor-mediated phage resistance often comes at a cost for
fitness.•Possible trade-offs may include attenuated virulence, and increased sensitivity to …

Evolutionary ecology of prokaryotic immune mechanisms

S van Houte, A Buckling, ER Westra - Microbiology and Molecular …, 2016 - Am Soc Microbiol
Bacteria have a range of distinct immune strategies that provide protection against
bacteriophage (phage) infections. While much has been learned about the mechanism of …

The disparate effects of bacteriophages on antibiotic-resistant bacteria

C Torres-Barceló - Emerging microbes & infections, 2018 - Taylor & Francis
Faced with the crisis of multidrug-resistant bacteria, bacteriophages, viruses that infect and
replicate within bacteria, have been reported to have both beneficial and detrimental effects …