Actin is among the most abundant proteins in eukaryotic cells and assembles into dynamic
filamentous networks regulated by many actin binding proteins. The actin cytoskeleton must …

Actin and its ability to polymerize into dynamic filaments is critical for the form and function of
cells throughout the body. While multiple proteins have been characterized as affecting actin …

Many of the best-studied actin regulatory proteins use non-covalent means to modulate the
properties of actin. Yet, actin is also susceptible to covalent modifications of its amino acids …

Actin is one of the most abundant proteins in eukaryotic cells and the main component of the
microfilament system. It plays essential roles in numerous cellular activities, including …

Actin oxidation is known to result in changes in cytoskeleton organization and dynamics.
Actin oxidation is clinically relevant since it occurs in the erythrocytes of sickle cell patients …

Redox sensitivity of actin toward an exogenous oxidative stress has recently been reported.
We report here the first evidence of in vivo actin redox regulation by a physiological source …

Hydrogen peroxide, coming from polymorphonuclear leukocytes, causes severe oxidative
injury on actin molecules with the disarrangement of cortical actin cytoskeleton followed by …

Actin is the major constituent of the cytoskeleton of almost all the eukaryotic cells. In vitro
experiments have indicated that oxidant-stressed nonmuscle mammalian cells undergo …

Protein carbonylation is a common feature in cells exposed to oxidants, leading to protein
dysfunction and protein aggregates. Actin, which is involved in manifold cellular processes …

The actin cytoskeleton of eukaryotic cells is a dynamic, fibrous network that is regulated by
the concerted action of actin-binding proteins (ABPs). In particular, rapid polarization of cells …