There is a long-standing interest in the role of endogenous opioid peptides in feeding
behavior and, in particular, in the modulation of food reward and palatability. Since drugs …

Our previous studies have shown that stimulation of mu-opioid receptors within the nucleus
accumbens preferentially enhances intake of palatable food containing sucrose and fat; …

Endogenous opioid peptides within the nucleus accumbens, a forebrain site critical for the
regulation of reward-related behavior, are believed to play an important role in the control of …

Nucleus accumbens μ-opioid stimulation causes marked increases in the intake of highly
palatable foods, such as a high-fat diet. However, to date there has been little examination of …

Rationale: Endogenous opioids have been implicated in the hedonic evaluation of food and
palatability. Opioids may also be involved in alcohol intake, as there is a positive correlation …

μ-Opioid systems in the medial shell of the nucleus accumbens contribute to hedonic impact
(“liking”) for sweetness, food, and drug rewards. But does the entire medial shell generate …

Microinjection of opioid agonists, such as morphine, into the nucleus accumbens shell
produces increases in eating behavior (ie 'wanting'for food). This study (1) reports direct …

Whether we 'like'and 'want'stimuli depends partially on opioid neurotransmission within the
nucleus accumbens. But how are 'liking'and 'wanting'organized within this neural substrate …

The neural basis of food sensory pleasure has become an increasingly studied topic in
neuroscience and psychology. Progress has been aided by the discovery of localized brain …

Food reward can be driven by separable mechanisms of hedonic impact (food 'liking') and
incentive motivation (food 'wanting'). Brain mu-opioid systems contribute crucially to both …