Despite impressive results from neuroscience research using rodent models, there is a
paucity of successful translation from preclinical findings to effective pharmacological …

Social factors have been shown to play a significant and lasting role in alcohol consumption.
Studying the role of social context on alcohol drinking is important to understand the factors …

Background Preclinical drug self-administration procedures are commonly used to
investigate expression, mechanisms, and treatment of substance use disorders. New …

Here, we describe a new model of voluntary alcohol drinking by group-housed mice. The
model employs sensor-equipped cages that track the behaviors of the individual animals via …

Abstract Background The National Institute on Drug Abuse (NIDA) recently released a
Request for Information (RFI) soliciting comments on nonhuman animal models of …

The use of animal models for substance use disorder (SUD) has made an important
contribution in the investigation of the behavioral and molecular mechanisms underlying …

Animal models of reinforcement have proven to be useful for understanding the
neurobiological mechanisms underlying drug addiction. Operant drug self-administration …

Rationale and objectives Social factors play a critical role in human drug addiction, and
humans often consume drugs together with their peers. In contrast, in traditional animal …

Substance use disorder (SUD) is comorbid with devastating health issues, social
withdrawal, and isolation. Successful clinical treatments for SUD have used social …

Genetically tractable animal models provide needed strategies to resolve the biological
basis of drug addiction. Intravenous self-administration (IVSA) is the gold standard for …