[HTML][HTML] Engineered CRISPR-Cas systems for the detection and control of antibiotic-resistant infections
Y Wu, D Battalapalli, MJ Hakeem, V Selamneni… - Journal of …, 2021 - Springer
Antibiotic resistance is spreading rapidly around the world and seriously impeding efforts to
control microbial infections. Although nucleic acid testing is widely deployed for the …
control microbial infections. Although nucleic acid testing is widely deployed for the …
[HTML][HTML] Harnessing the CRISPR-Cas systems to combat antimicrobial resistance
The emergence of antimicrobial-resistant (AMR) bacteria has become one of the most
serious threats to global health, necessitating the development of novel antimicrobial …
serious threats to global health, necessitating the development of novel antimicrobial …
CRISPR-Cas system as a promising player against bacterial infection and antibiotic resistance
M Abavisani, R Khayami, M Hoseinzadeh… - Drug Resistance …, 2023 - Elsevier
The phenomenon of antibiotic resistance (AR) and its increasing global trends and
destructive waves concerns patients and the healthcare system. In order to combat AR, it is …
destructive waves concerns patients and the healthcare system. In order to combat AR, it is …
How CRISPR-Cas system could be used to combat antimicrobial resistance
Rapid emergence of antibiotic-resistant bacteria has made it harder for us to combat
infectious diseases and to develop new antibiotics. The clustered regularly interspaced short …
infectious diseases and to develop new antibiotics. The clustered regularly interspaced short …
Nucleic acid detection using CRISPR/Cas biosensing technologies
For infectious diseases, rapid and accurate identification of the pathogen is critical for
effective management and treatment, but diagnosis remains challenging, particularly in …
effective management and treatment, but diagnosis remains challenging, particularly in …
[HTML][HTML] CRISPR-cas system: biological function in microbes and its use to treat antimicrobial resistant pathogens
The development of antibiotic resistance in bacteria is a major public health threat. Infection
rates of resistant pathogens continue to rise against nearly all antimicrobials, which has led …
rates of resistant pathogens continue to rise against nearly all antimicrobials, which has led …
CRISPR-based antibacterials: transforming bacterial defense into offense
AC Greene - Trends in biotechnology, 2018 - cell.com
The development of antimicrobial-resistant (AMR) bacteria poses a serious worldwide
health concern. CRISPR-based antibacterials are a novel and adaptable method for …
health concern. CRISPR-based antibacterials are a novel and adaptable method for …
Current and future prospects for CRISPR‐based tools in bacteria
ML Luo, RT Leenay, CL Beisel - Biotechnology and …, 2016 - Wiley Online Library
ABSTRACT CRISPR‐Cas systems have rapidly transitioned from intriguing prokaryotic
defense systems to powerful and versatile biomolecular tools. This article reviews how these …
defense systems to powerful and versatile biomolecular tools. This article reviews how these …
CRISPR-Cas9 technology: applications in genome engineering, development of sequence-specific antimicrobials, and future prospects
C de la Fuente-Núñez, TK Lu - Integrative Biology, 2017 - academic.oup.com
The development of CRISPR-Cas9 technology has revolutionized our ability to edit DNA
and to modulate expression levels of genes of interest, thus providing powerful tools to …
and to modulate expression levels of genes of interest, thus providing powerful tools to …
[HTML][HTML] Development of CRISPR-Cas13a-based antimicrobials capable of sequence-specific killing of target bacteria
K Kiga, XE Tan, R Ibarra-Chávez, S Watanabe… - Nature …, 2020 - nature.com
The emergence of antimicrobial-resistant bacteria is an increasingly serious threat to global
health, necessitating the development of innovative antimicrobials. Here we report the …
health, necessitating the development of innovative antimicrobials. Here we report the …