The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) trial: first randomized placebo-controlled study of myoblast transplantation

P Menasché, O Alfieri, S Janssens, W McKenna… - Circulation, 2008 - Am Heart Assoc
Background—Phase I clinical studies have demonstrated the feasibility of implanting
autologous skeletal myoblasts in postinfarction scars. However, they have failed to …

Skeletal myoblasts as a therapeutic agent

P Menasché - Progress in cardiovascular diseases, 2007 - Elsevier
Cell transplantation is emerging as a new treatment designed to improve the poor outcome
of patients with cardiac failure. Its rationale is that implantation of contractile cells into …

Safety and feasibility of autologous myoblast transplantation in patients with ischemic cardiomyopathy: four-year follow-up

N Dib, RE Michler, FD Pagani, S Wright, DJ Kereiakes… - Circulation, 2005 - Am Heart Assoc
Background—Successful autologous skeletal myoblast transplantation into infarcted
myocardium in a variety of animal models has demonstrated improvement in cardiac …

Feasibility and safety of autologous myoblast transplantation in patients with ischemic cardiomyopathy

N Dib, P McCarthy, A Campbell, M Yeager… - Cell …, 2005 - journals.sagepub.com
Successful autologous skeletal myoblast transplantation into infarcted myocardium in a
variety of animal models has demonstrated improvement in cardiac function. We evaluated …

Autologous skeletal myoblast transplantation for severe postinfarction left ventricular dysfunction

P Menasché, AA Hagège, JT Vilquin, M Desnos… - Journal of the American …, 2003 - jacc.org
Objectives: This phase I trial was designed to assess the feasibility and safety of autologous
skeletal myoblast transplantation in patients with severe ischemic cardiomyopathy …

[HTML][HTML] Autologous skeletal myoblast transplantation in patients with nonacute myocardial infarction: 1-year follow-up

JJ Gavira, J Herreros, A Perez… - The Journal of thoracic …, 2006 - Elsevier
OBJECTIVE: To determine the feasibility and safety of skeletal myoblast transplantation in
patients with chronic myocardial infarction undergoing coronary artery bypass grafting …

Catheter-based intramyocardial injection of autologous skeletal myoblasts as a primary treatment of ischemic heart failure: clinical experience with six-month follow-up

PC Smits, RJM van Geuns, D Poldermans… - Journal of the American …, 2003 - jacc.org
Objectives: We report on the procedural and six-month results of the first percutaneous and
stand-alone study on myocardial repair with autologous skeletal myoblasts. Background …

Skeletal myoblast for cell therapy

P Menasché - Coronary artery disease, 2005 - journals.lww.com
After a decade of experimental work, skeletal myoblast transplantation has now entered the
clinical arena as a potentially new means of improving the function of the failing heart …

A double-blind, randomized, controlled, multicenter study to assess the safety and cardiovascular effects of skeletal myoblast implantation by catheter delivery in …

TJ Povsic, CM O'Connor, T Henry, A Taussig… - American heart …, 2011 - Elsevier
BACKGROUND: We sought to determine the safety and preliminary efficacy of transcatheter
intramyocardial administration of myoblasts in patients with heart failure (HF). METHODS …

Skeletal myoblast transplantation in ischemic heart failure: long-term follow-up of the first phase I cohort of patients

AA Hagege, JP Marolleau, JT Vilquin, A Alhéritiere… - Circulation, 2006 - Am Heart Assoc
Background—Skeletal myoblast (SM) transplantation (Tx) in a post-myocardial infarction
(MI) scar experimentally improves left ventricular (LV) ejection fraction (EF). Short-term …