Addressing the need for effective cancer chemotherapy with low adverse effects has been
partially possible through innovative therapeutic approaches combining chemotherapeutics …

Co-delivery of therapeutic agents and small interfering RNA (siRNA) can be achieved by a
suitable nanovehicle. In this work, the solubility and bioavailability of curcumin (Cur) were …

Aberrant gene expression can trigger several vital molecular events that not only result in
carcinogenesis but also cause chemoresistance, metastasis and relapse. Gene-based …

Finding out predisposition and makeup alterations in cancer cells has prompted the
exploration of exogenous small interference RNA (siRNA) as a therapeutic agent to deal …

Chemotherapy using natural compounds, such as resveratrol, curcumin, paclitaxel,
docetaxel, etoposide, doxorubicin, and camptothecin, is of importance in cancer therapy …

Nanotechnology-based combination anticancer therapy offers novel approaches to
overcome the limitations of single-agent administration. The emerging siRNA technology …

Because of the complexity of cancer, combination therapy is becoming increasingly
important to overcome multidrug resistance in cancer and to enhance apoptosis. Cancer …

Traditional chemotherapeutic agents have long been associated with serious drawbacks
due to the heterogeneity and complexity of human cancer. One of the major hurdles …

RNA interference (RNAi) is emerging as a powerful approach in cancer treatment. siRNA is
an important RNAi tool that can be designed to specifically silence the expression of genes …

Chemotherapeutic agents have certain limitations when it comes to treating cancer, the most
important being severe side effects along with multidrug resistance developed against them …