The common denominators of Parkinson's disease pathogenesis and methamphetamine abuse

B Vincent, M Shukla - Current Neuropharmacology, 2023 - hal.science
The pervasiveness and mortality associated with methamphetamine abuse has doubled
during the past decade suggesting a possible worldwide substance use crisis. Epitomizing …

Methamphetamine-induced neurotoxicity: the road to Parkinson's disease

B Thrash, K Thiruchelvan, M Ahuja… - Pharmacological …, 2009 - Elsevier
Studies have implicated methamphetamine exposure as a contributor to the development of
Parkinson's disease. There is a significant degree of striatal dopamine depletion produced …

Is methamphetamine abuse a risk factor in parkinsonism?

TR Guilarte - Neurotoxicology, 2001 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder with increased incidence in
individuals beyond 50 years of age. The etiology of PD is currently not known, but it appears …

Methamphetamine causes degeneration of dopamine cell bodies and terminals of the nigrostriatal pathway evidenced by silver staining

S Ares-Santos, N Granado, I Espadas… - …, 2014 - nature.com
Methamphetamine is a widely abused illicit drug. Recent epidemiological studies showed
that methamphetamine increases the risk for developing Parkinson's disease (PD) in …

Methamphetamine and Parkinson′ s Disease

N Granado, S Ares-Santos, R Moratalla - Parkinson's disease, 2013 - Wiley Online Library
Parkinson′ s disease (PD) is a neurodegenerative disorder predominantly affecting the
elderly. The aetiology of the disease is not known, but age and environmental factors play …

Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse

R Perfeito, T Cunha-Oliveira, AC Rego - Free Radical Biology and …, 2012 - Elsevier
Parkinson disease (PD) is a chronic and progressive neurological disease associated with a
loss of dopaminergic neurons. In most cases the disease is sporadic but genetically …

Neuroprotection or neurotoxicity of illicit drugs on Parkinson's disease

C Ferreira, C Almeida, S Tenreiro, A Quintas - Life, 2020 - mdpi.com
Parkinson's Disease (PD) is currently the most rapid growing neurodegenerative disease
and over the past generation, its global burden has more than doubled. The onset of PD can …

Reprint of: revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of …

R Perfeito, T Cunha-Oliveira, AC Rego - Free Radical Biology and …, 2013 - Elsevier
Parkinson disease (PD) is a chronic and progressive neurological disease associated with a
loss of dopaminergic neurons. In most cases the disease is sporadic but genetically …

The methamphetamine experience: a NIDA partnership

GR Hanson, KS Rau, AE Fleckenstein - Neuropharmacology, 2004 - Elsevier
The neurotoxic properties of the amphetamines such as methamphetamine (METH) were
originally described about the time of the National Institute on Drug Abuse's organization, in …

The role of α-synuclein in methamphetamine-induced neurotoxicity

M Wu, H Su, M Zhao - Neurotoxicity Research, 2021 - Springer
Methamphetamine (METH), a highly addictive psychostimulant, is the second most widely
used illicit drug. METH produces damage dopamine neurons and apoptosis via multiple …