Frailty, fitness and late-life mortality in relation to chronological and biological age
Background People age at remarkably different rates, but how to estimate trajectories of
senescence is controversial. Methods In a secondary analysis of a representative cohort of …
senescence is controversial. Methods In a secondary analysis of a representative cohort of …
Is frailty a stable predictor of mortality across time? Evidence from the Cognitive Function and Ageing Studies
Background age-specific mortality reduction has been accompanied by a decrease in the
prevalence of some diseases and an increase in others. Whether populations are becoming …
prevalence of some diseases and an increase in others. Whether populations are becoming …
The estimation of relative fitness and frailty in community-dwelling older adults using self-report data
Background. While on average health declines with age, it also becomes more variable with
age. As a consequence of this marked variability, it becomes more important as people age …
age. As a consequence of this marked variability, it becomes more important as people age …
A comparison of two approaches to measuring frailty in elderly people
K Rockwood, M Andrew… - The Journals of …, 2007 - academic.oup.com
Background. Many definitions of frailty exist, but few have been directly compared. We
compared the relationship between a definition of frailty based on a specific phenotype with …
compared the relationship between a definition of frailty based on a specific phenotype with …
A global clinical measure of fitness and frailty in elderly people
Background: There is no single generally accepted clinical definition of frailty. Previously
developed tools to assess frailty that have been shown to be predictive of death or need for …
developed tools to assess frailty that have been shown to be predictive of death or need for …
Cognitive impairment improves the predictive validity of the phenotype of frailty for adverse health outcomes: the three‐city study
JA Ávila‐Funes, H Amieva… - Journal of the …, 2009 - Wiley Online Library
OBJECTIVES: To determine whether adding cognitive impairment to frailty improves its
predictive validity for adverse health outcomes. DESIGN: Four‐year longitudinal study …
predictive validity for adverse health outcomes. DESIGN: Four‐year longitudinal study …
Changes in relative fitness and frailty across the adult lifespan: evidence from the Canadian National Population Health Survey
Background The prevalence of frailty increases with age in older adults, but frailty is largely
unreported for younger adults, where its associated risk is less clear. Furthermore, less is …
unreported for younger adults, where its associated risk is less clear. Furthermore, less is …
Measures of frailty in population-based studies: an overview
Background Although research productivity in the field of frailty has risen exponentially in
recent years, there remains a lack of consensus regarding the measurement of this …
recent years, there remains a lack of consensus regarding the measurement of this …
Frailty index as a measure of biological age in a Chinese population
WB Goggins, J Woo, A Sham… - The Journals of …, 2005 - academic.oup.com
Background. The concept of a frailty index, developed in Canadian elderly populations as
an indicator of biological age as opposed to chronological age, was tested in an elderly …
an indicator of biological age as opposed to chronological age, was tested in an elderly …
What are frailty instruments for?
Frailty is measured to understand its nature and biology, to aid diagnosis and care planning,
to measure outcomes and to stratify risk. Such goals oblige two types of frailty measures—for …
to measure outcomes and to stratify risk. Such goals oblige two types of frailty measures—for …