Predicting Alzheimer's Disease with Interpretable Machine Learning

M Jia, Y Wu, C Xiang, Y Fang - Dementia and Geriatric Cognitive …, 2023 - karger.com
Introduction: This study aimed to develop novel machine learning models for predicting
Alzheimer's disease (AD) and identify key factors for targeted prevention. Methods: We …

Early prediction of Alzheimer's disease and related dementias using real‐world electronic health records

Q Li, X Yang, J Xu, Y Guo, X He, H Hu… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction This study aims to explore machine learning (ML) methods for early prediction
of Alzheimer's disease (AD) and related dementias (ADRD) using the real‐world electronic …

[HTML][HTML] An explainable machine learning approach for Alzheimer's disease classification

AS Alatrany, W Khan, A Hussain, H Kolivand… - Scientific Reports, 2024 - nature.com
The early diagnosis of Alzheimer's disease (AD) presents a significant challenge due to the
subtle biomarker changes often overlooked. Machine learning (ML) models offer a …

[HTML][HTML] An explainable machine learning based prediction model for Alzheimer's disease in China longitudinal aging study

L Yue, W Chen, S Liu, S Chen, S Xiao - Frontiers in Aging …, 2023 - frontiersin.org
Alzheimer's disease (AD) is the most common cause of dementia. Accurate prediction and
diagnosis of AD and its prodromal stage, ie, mild cognitive impairment (MCI), is essential for …

Machine learning for the life-time risk prediction of Alzheimer's disease: a systematic review

TW Rowe, IK Katzourou… - Brain …, 2021 - academic.oup.com
Alzheimer's disease is a neurodegenerative disorder and the most common form of
dementia. Early diagnosis may assist interventions to delay onset and reduce the …

[HTML][HTML] A machine learning approach for early diagnosis of cognitive impairment using population-based data

WY Tan, C Hargreaves, C Chen… - Journal of Alzheimer's …, 2023 - content.iospress.com
Background: The major mechanisms of dementia and cognitive impairment are vascular and
neurodegenerative processes. Early diagnosis of cognitive impairment can facilitate timely …

[HTML][HTML] Explainable machine learning aggregates polygenic risk scores and electronic health records for Alzheimer's disease prediction

XR Gao, M Chiariglione, K Qin, K Nuytemans… - Scientific reports, 2023 - nature.com
Alzheimer's disease (AD) is the most common late-onset neurodegenerative disorder.
Identifying individuals at increased risk of developing AD is important for early intervention …

[HTML][HTML] Predicting early Alzheimer's with blood biomarkers and clinical features

ME AlMansoori, S Jemimah, F Abuhantash… - Scientific Reports, 2024 - nature.com
Alzheimer's disease (AD) is an incurable neurodegenerative disorder that leads to
dementia. This study employs explainable machine learning models to detect dementia …

[HTML][HTML] Differences in cohort study data affect external validation of artificial intelligence models for predictive diagnostics of dementia-lessons for translation into …

C Birkenbihl, MA Emon, H Vrooman, S Westwood… - EPMA Journal, 2020 - Springer
Artificial intelligence (AI) approaches pose a great opportunity for individualized, pre-
symptomatic disease diagnosis which plays a key role in the context of personalized …

Machine learning for modeling the progression of Alzheimer disease dementia using clinical data: a systematic literature review

S Kumar, I Oh, S Schindler, AM Lai, PRO Payne… - JAMIA …, 2021 - academic.oup.com
Objective Alzheimer disease (AD) is the most common cause of dementia, a syndrome
characterized by cognitive impairment severe enough to interfere with activities of daily life …