In vitro Evaluation of Acyclovir/Chitosan Floating Systems

R Ruiz-Caro, MD Veiga - Materials, 2010 - mdpi.com
Chitosan (CS) floating lyophilized formulations (L) for gastric drug delivery of acyclovir (ACV)
have been developed. The freeze-dried formulations were obtained from acidic aqueous …

Development of mucoadhesive floating hollow beads of acyclovir with gastroretentive properties

D Svirskis, A Seyfoddin, S Chalabi… - Pharmaceutical …, 2014 - Taylor & Francis
This study aimed at improving the oral bioavailability of acyclovir (ACV) through
incorporating it into gastroretentive dosage form based on floating hollow chitosan beads …

Mucoadhesive tablets for controlled release of acyclovir

R Ruiz-Caro, M Gago-Guillan… - Chemical and …, 2012 - jstage.jst.go.jp
Mucoadhesive chitosan (CS) and/or hydroxypropyl-methylcellulose (HPMC) tablets for
gastric drug delivery of acyclovir (ACV) have been developed in order to improve the ACV …

Acyclovir-loaded chitosan microspheres for gastroretention: development and evaluation

S Md, A Ahuja, RK Khar, S Baboota, J Ali… - Journal of dispersion …, 2011 - Taylor & Francis
Mucoadhesive chitosan microspheres of acyclovir were prepared to prolong the gastric
residence time using simple emulsification phase separation technique. The particle …

Development and evaluation of a monolithic floating drug delivery system for acyclovir

N Tavakoli, J Varshosaz, F Dorkoosh… - Chemical and …, 2012 - jstage.jst.go.jp
Acyclovir (ACV), a model drug for this study, is one of the most effective drugs against
viruses of the herpes group. Absorption of orally administered ACV is variable and …

The effect of amphiphilic N, N, N-trimethyl-O-octadecyl chitosan on the oral bioavailability of acyclovir

H Chen, J Wang, C Liu, Y Wang, Y Fu, D Wang… - Journal of Drug Delivery …, 2019 - Elsevier
Acyclovir (ACV), an analog of 2′-deoxyguanosine, exhibits poor bioavailability due to
limited permeability. In this study, the aim was to improve the bioavailability and permeability …

Formulation and evaluation of gastro retentive mucoadhesive sustained release pellets of Acyclovir

SM Gite, SS Bhusari, A Sav… - International Journal of …, 2012 - search.proquest.com
Acyclovir is an antiviral drug, belonging to the deoxyguanosine family, widely prescribed for
the treatment of herpes simplex viral infections, as well as in the treatment of herpes zoster …

Mucoadhesive Microspheres for Gastroretentive Delivery of Acyclovir: In Vitro and In Vivo Evaluation

S Dhaliwal, S Jain, HP Singh, AK Tiwary - The AAPS journal, 2008 - Springer
The aim of the present investigation was to evaluate the potential use of mucoadhesive
microspheres for gastroretentive delivery of acyclovir. Chitosan, thiolated chitosan, Carbopol …

Formulation and evaluation of sustained release gastro-retentive drug delivery system of acyclovir leading to enhanced bioavailability

SK Mishra, S Khatri - British Journal of Pharmaceutical …, 2015 - library.eprintdigipress.com
Objective: The objective was formulation and characterization of low-density gastro-retentive
microspheres of Acyclovir (ACV) using hydroxyl propyl methyl cellulose to enhanced …

[PDF][PDF] Formulation and evaluation of floating gastroretentive capsules of acyclovir with piperine as a bioenhancer

S Khatri, FJ Ahmed, P Rai - The Pharma Innovation, 2015 - academia.edu
The aim of the present investigation was to develop and evaluate the sustained release
hydrodynamic balanced systems for acyclovir using hydrocolloid polymers such as hydroxy …