Long noncoding RNAs as novel biomarkers have a promising future in cancer diagnostics

T Shi, G Gao, Y Cao - Disease markers, 2016 - Wiley Online Library
Cancers have a high mortality rate due to lack of suitable specific early diagnosis tumor
biomarkers. Emerging evidence is accumulating that lncRNAs (long noncoding RNAs) are …

Long noncoding RNAs as biomarkers in cancer

L Bolha, M Ravnik-Glavač, D Glavač - Disease markers, 2017 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a relatively well‐characterized class of noncoding
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …

[HTML][HTML] Long noncoding RNAs as promising biomarkers in cancer

O Beylerli, I Gareev, A Sufianov, T Ilyasova… - Non-coding RNA …, 2022 - Elsevier
Despite many advances in diagnosis and therapy (surgery, radiation therapy,
chemotherapy), cancer remains one of the most important public health problems …

Long noncoding RNAs biomarker‐based cancer assessment

M Sarfi, M Abbastabar, E Khalili - Journal of cellular physiology, 2019 - Wiley Online Library
Cancer diagnosis have mainly relied on the incorporation of molecular biomarkers as part of
routine diagnostic tool. The molecular alteration ranges from those involving DNA, RNA …

Long noncoding RNAs as new architects in cancer epigenetics, prognostic biomarkers, and potential therapeutic targets

D Meseure, K Drak Alsibai, A Nicolas… - BioMed research …, 2015 - Wiley Online Library
Recent advances in genome‐wide analysis have revealed that 66% of the genome is
actively transcribed into noncoding RNAs (ncRNAs) while less than 2% of the sequences …

[HTML][HTML] Long non-coding RNA in cancer

N Hauptman, D Glavač - International journal of molecular sciences, 2013 - mdpi.com
Long non-coding RNAs (lncRNAs) are pervasively transcribed in the genome and are
emerging as new players in tumorigenesis due to their various functions in transcriptional …

Potential of long non‐coding RNAs in cancer patients: from biomarkers to therapeutic targets

S Chandra Gupta… - International journal of …, 2017 - Wiley Online Library
Because of high specificity and easy detection in the tissues, serum, plasma, urine and
saliva, interest in exploring the potential of long non‐coding RNAs (lncRNAs) in cancer …

Long noncoding RNAs: a potential novel class of cancer biomarkers

AA Yarmishyn, IV Kurochkin - Frontiers in genetics, 2015 - frontiersin.org
Long noncoding RNAs (lncRNAs) are a novel class of RNA molecules defined as transcripts
longer than 200 nucleotides that lack protein coding potential. They constitute a major, but …

Emerging role of oncogenic long noncoding RNA as cancer biomarkers

M Aprile, V Costa, A Cimmino… - International journal of …, 2023 - Wiley Online Library
The view of long noncoding RNAs as nonfunctional “garbage” has been definitely outdated
by the large body of evidence indicating this class of ncRNAs as “golden junk”, especially in …

The clinical relevance of long non-coding RNAs in cancer

A Silva, M Bullock, G Calin - Cancers, 2015 - mdpi.com
Non-coding RNAs have long been associated with cancer development and progression,
and since their earliest discovery, their clinical potential in identifying and characterizing the …