Major progress in studying the biology of schistosomes had been achieved since the late
1960s with the successful laboratory cultivation of the parasite's life cycle stages in the …

Schistosomiasis, or bilharzias, is a neglected disease that remains a considerable public
health problem in tropical and subtropical regions. This parasitic disease is the most …

Schistosomiasis is a chronic parasitic disease affecting about 207 million people in the
world. It still represents a major health problem in many tropical and sub-tropical countries …

Schistosomiasis affects 200 million individuals in underdeveloped and developing regions
and is a growing concern for travelers worldwide. There has been evidence of resistance to …

Chemotherapy based on repeated doses of praziquantel remains the most effective control
strategy against schistosomiasis, a neglected tropical disease caused by platyhelminths of …

In September 2022, the Drug Discovery Unit at the University of Dundee, UK, organised an
international meeting at the Wellcome Collection in London to explore the current clinical …

It has been often observed that the chemotherapeutic armamentarium against an important
disease such as schistosomiasis consists of just one drug, praziquantel. Thus, development …

Praziquantel has remained the drug of choice for schistosomiasis chemotherapy for almost
40 years. The pressing need to develop a new antischistosomal drug may necessitate …

Since no vaccine exists against schistosomiasis and the molluscs acting as intermediate
hosts are not easy to attack, chemotherapy is the main approach for schistosomiasis control …

No major changes have occurred during the past 20 years regarding the therapeutic tools
available to the clinician for the treatment of schistosomiasis. If anything, the two drugs …