Beyond their role as a cellular powerhouse, mitochondria are emerging as integral players
in molecular signaling and cell fate determination through reactive oxygen species (ROS) …

Mitochondria are essential signaling organelles that regulate a broad range of cellular
processes and thereby heart function. Multiple mechanisms participate in the …

Cardiovascular diseases (CVDs) are serious public health issues and are responsible for
nearly one-third of global deaths. Mitochondrial dysfunction is accountable for the …

Mitochondria are essential to providing ATP, thereby satisfying the energy demand of the
incessant electrical activity and contractile action of cardiac muscle. Emerging evidence …

Mitochondrial dysfunction characterized by impaired bioenergetics, oxidative stress and
aldehydic load is a hallmark of heart failure. Recently, different research groups have …

The mitochondrion is a vital component in cellular energy metabolism and intracellular
signaling processes. Mitochondria are involved in a myriad of complex signaling cascades …

Reactive oxygen species (ROS) have been implicated in a variety of age-related diseases,
including multiple cardiovascular disorders. However, translation of ROS scavengers …

Mitochondrial dysfunction is considered as a crucial contributory factor in cardiac pathology.
This has highlighted the therapeutic potential of targeting mitochondria to prevent or treat …

Mitochondria play an important role in maintaining cardiac homeostasis by supplying the
major energy required for cardiac excitation–contraction coupling as well as controlling the …

Mitochondrial dysfunction has been implicated in the development of heart failure. Oxidative
metabolism in mitochondria is the main energy source of the heart, and the inability to …