Therapeutic potential of antimicrobial peptides in polymicrobial biofilm-associated infections

G Batoni, G Maisetta, S Esin - International Journal of Molecular Sciences, 2021 - mdpi.com
It is widely recognized that many chronic infections of the human body have a polymicrobial
etiology. These include diabetic foot ulcer infections, lung infections in cystic fibrosis …

Potential application of antimicrobial peptides in the treatment of bacterial biofilm infections

N Strempel, J Strehmel… - Current pharmaceutical …, 2015 - ingentaconnect.com
The increasing prevalence of persistent biofilm infections, such as wound infections, chronic
lung infections or medical device-related infections, which usually tolerate conventional …

Use of antimicrobial peptides against microbial biofilms: advantages and limits

G Batoni, G Maisetta… - Current medicinal …, 2011 - ingentaconnect.com
The formation of surface-attached cellular agglomerates, the so-called biofilms, contributes
significantly to bacterial resistance to antibiotics and innate host defenses. Bacterial biofilms …

Combination strategies to enhance the efficacy of antimicrobial peptides against bacterial biofilms

L Grassi, G Maisetta, S Esin, G Batoni - Frontiers in Microbiology, 2017 - frontiersin.org
The great clinical significance of biofilm-associated infections and their inherent
recalcitrance to antibiotic treatment urgently demand the development of novel antibiofilm …

[HTML][HTML] Antimicrobial peptides as potential anti-biofilm agents against multidrug-resistant bacteria

PY Chung, R Khanum - Journal of microbiology, immunology and infection, 2017 - Elsevier
Bacterial resistance to commonly used drugs has become a global health problem, causing
increased infection cases and mortality rate. One of the main virulence determinants in many …

A comprehensive guide on screening and selection of a suitable AMP against biofilm-forming bacteria

A Anurag Anand, A Amod, S Anwar… - Critical Reviews in …, 2023 - Taylor & Francis
Lately, antimicrobial resistance (AMR) is increasing at an exponential rate making it
important to search alternatives to antibiotics in order to combat multi-drug resistant (MDR) …

[HTML][HTML] Antimicrobial peptides and their interaction with biofilms of medically relevant bacteria

G Batoni, G Maisetta, S Esin - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
Biofilm-associated infections represent one of the major threats of modern medicine. Biofilm-
forming bacteria are encased in a complex mixture of extracellular polymeric substances …

Antimicrobial peptides and their applications in biomedical sector

A Sultana, H Luo, S Ramakrishna - Antibiotics, 2021 - mdpi.com
In a report by WHO (2014), it was stated that antimicrobial resistance is an arising challenge
that needs to be resolved. This resistance is a critical issue in terms of disease or infection …

Delivery systems for antimicrobial peptides

R Nordström, M Malmsten - Advances in colloid and interface science, 2017 - Elsevier
Due to rapidly increasing resistance development against conventional antibiotics, finding
novel approaches for the treatment of infections has emerged as a key health issue …

AMPs as anti-biofilm agents for human therapy and prophylaxis

H Shahrour, R Ferrer-Espada, I Dandache… - … Peptides: Basics for …, 2019 - Springer
Microbial cells show a strong natural tendency to adhere to surfaces and to colonize them by
forming complex communities called biofilms. In this growth mode, biofilm-forming cells …