Fluid administration is a key intervention in hemodynamic resuscitation. Timely expansion
(or restoration) of plasma volume may prevent tissue hypoxia and help to preserve organ …

Among critically ill adults, sepsis remains both common and lethal. In addition to antibiotics
and source control, fluid resuscitation is a fundamental sepsis therapy. The physiology of …

Key questions remain unresolved regarding the advantages and limitations of colloids for
fluid resuscitation despite extensive investigation. Elucidation of these questions has been …

Objective: To assess whether resuscitation with albumin-containing solutions, compared
with other fluids, is associated with lower mortality in patients with sepsis. Data Sources …

Fluid administration should be tailored to patient characteristics. Synthetic colloids should be
avoided when possible, especially in patients at risk for kidney injury. In critically ill patients …

Purpose To determine the effect of random assignment to fluid resuscitation with albumin or
saline on organ function and mortality in patients with severe sepsis. Methods Pre-defined …

Background Human albumin solutions are used in a range of medical and surgical
problems. Licensed indications are the emergency treatment of shock and other conditions …

Background Early fluid resuscitation is vital to patients with sepsis. However, the choice of
fluid has been a hot topic of discussion. The objective of this study was to evaluate whether …

Objective Positive fluid balance is common among critically ill patients and leads to worse
outcomes, particularly in sepsis, acute respiratory distress syndrome, and acute kidney …

Background Although previous studies have suggested the potential advantages of albumin
administration in patients with severe sepsis, its efficacy has not been fully established …