Advances in purification, modification, and application of extracellular vesicles for novel clinical treatments

Y Matsuzaka, R Yashiro - Membranes, 2022 - mdpi.com
Extracellular vesicles (EV) are membrane vesicles surrounded by a lipid bilayer membrane
and include microvesicles, apoptotic bodies, exosomes, and exomeres. Exosome …

Stem cell-derived exosomes and nanovesicles: promotion of cell proliferation, migration, and anti-senescence for treatment of wound damage and skin ageing

H Cha, S Hong, JH Park, HH Park - Pharmaceutics, 2020 - mdpi.com
Extracellular vesicles (EVs), such as exosomes, are nano-sized vesicles derived from
endocytic membranes and contain biomolecules such as proteins, lipids, RNAs, and DNAs …

The emerging role of exosomes in the treatment of human disorders with a special focus on mesenchymal stem cells-derived exosomes

S Ghafouri-Fard, V Niazi, BM Hussen… - Frontiers in Cell and …, 2021 - frontiersin.org
Extracellular vesicles (EVs) are produced by diverse eukaryotic and prokaryotic cells. They
have prominent roles in the modulation of cell-cell communication, inflammation versus …

Current knowledge and future perspectives on mesenchymal stem cell-derived exosomes as a new therapeutic agent

HS Joo, JH Suh, HJ Lee, ES Bang, JM Lee - International journal of …, 2020 - mdpi.com
Mesenchymal stem cells (MSCs) are on the cusp of regenerative medicine due to their
differentiation capacity, favorable culture conditions, ability to be manipulated in vitro, and …

Emerging role of mesenchymal stem cell-derived exosomes in regenerative medicine

T Zhao, F Sun, J Liu, T Ding, J She… - Current stem cell …, 2019 - ingentaconnect.com
Background: Recent studies have shown the great value of cell therapy over the past few
decades. Mesenchymal stem cells (MSCs) have been reported to treat various degenerative …

Exosomes: new molecular targets of diseases

S Samanta, S Rajasingh, N Drosos, Z Zhou… - Acta Pharmacologica …, 2018 - nature.com
Extracellular vesicles (EVs) comprise apoptotic bodies, microvesicles and exosomes, and
they perform as key regulators in cell-to-cell communication in normal as well as diseased …

Therapeutic Applications of Stem Cell-Derived Exosomes

OAAY Abdulmalek, KH Husain, HKAA AlKhalifa… - International Journal of …, 2024 - mdpi.com
Exosomes are extracellular vesicles of endosomal origin, ranging from 30 to 150 nm in
diameter, that mediate intercellular transfer of various biomolecules, such as proteins, lipids …

Concise review: MSC-derived exosomes for cell-free therapy

DG Phinney, MF Pittenger - Stem cells, 2017 - academic.oup.com
Mesenchymal stem cell transplantation is undergoing extensive evaluation as a cellular
therapy in human clinical trials. Because MSCs are easily isolated and amenable to culture …

Mesenchymal stem cell‐derived extracellular vesicles and their therapeutic potential

AG Zhao, K Shah, B Cromer… - Stem cells international, 2020 - Wiley Online Library
Extracellular vesicles (EVs) are cell‐derived membrane‐bound nanoparticles, which act as
shuttles, delivering a range of biomolecules to diverse target cells. They play an important …

NANOmetric BIO-banked MSC-derived exosome (NANOBIOME) as a novel approach to regenerative medicine

B Codispoti, M Marrelli, F Paduano… - Journal of Clinical …, 2018 - mdpi.com
Mesenchymal stem cells (MSCs) are well known for their great potential in clinical
applications. In fact, MSCs can differentiate into several cell lineages and show paracrine …