Summary microRNAs (miRNAs) are a class of small, noncoding RNAs that regulate the
stability or translation of mRNA transcripts. Although recent work has implicated miRNAs in …

The regulatory mechanisms of circadian rhythms have been studied primarily at the level of
the transcription–translation feedback loops of protein-coding genes. Regulatory modules …

MicroRNAs (miRNAs) interact with 3′ untranslated region (UTR) elements of target genes
to regulate mRNA stability or translation and thus play a role in regulating many different …

Background Circadian clocks coordinate an organism's activities and regulate metabolic
homeostasis in relation to daily environmental changes, most notably light/dark cycles. As in …

Evolved under the selective pressures of a 24-h world, circadian timekeeping mechanisms
are present in virtually all living organisms to coordinate daily rhythms in physiology and …

Mammalian circadian rhythms are synchronized to the external time by daily resetting of the
suprachiasmatic nucleus (SCN) in response to light. As the master circadian pacemaker, the …

To investigate the potential role of microRNA (miRNA) in the regulation of circadian rhythm,
we performed microarray-based expression profiling study of both miRNA and mRNA in …

Little is known about the contribution of translational control to circadian rhythms. To address
this issue and in particular translational control by microRNAs (miRNAs), we knocked down …

Background MicroRNAs (miRNAs) are short non-coding RNA molecules that target mRNAs
to control gene expression by attenuating the translational efficiency and stability of …

Several biological functions in mammals are regulated in a circadian fashion. The molecular
mechanisms orchestrating these circadian rhythms have been unravelled. The biological …