Activation of the cyclic GMP‐AMP synthase‐stimulator of the interferon gene (cGAS‐STING)
pathway is a potent anticancer immunotherapeutic strategy, and the induction of pyroptosis …

The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon (STING) pathway is a key
mediator of innate immunity involved in cancer development and treatment. The roles of …

Promoting innate immunity through pyroptosis induction or the cyclic GMP‐AMP synthase‐
stimulator of interferon gene (cGAS‐STING) pathway activation has emerged as a potent …

The cGAS‐STING pathway, as a vital innate immune signaling pathway, has attracted
considerable attention in tumor immunotherapy research. However, STING agonists are …

Overcoming the resistance to apoptosis and immunosuppression of tumor cells is a
significant challenge in augmenting the effect of cancer immunotherapy. Pyroptosis, a lytic …

Pyroptosis, a newly characterized form of immunogenic cell death, is attracting increasing
attention as a promising approach to cancer immunotherapy. However, biocompatible …

Pyroptosis refers to the process of gasdermin-mediated lytic programmed cell death (PCD)
characterized by the release of pro-inflammatory cytokines. Our knowledge of pyroptosis has …

Pyroptosis as a lytic and inflammatory form of cell death is a powerful tool to fight against
cancer. However, pyroptosis is usually activated by chemotherapeutic drugs, which limits its …

An ideal cancer treatment should not only destroy primary tumors but also improve the
immunogenicity of the tumor microenvironment to achieve a satisfactory anti‐tumor immune …

The platinum (IV) prodrug trans, trans, trans-[Pt (N3) 2 (OH) 2 (py) 2](1) is stable and non-
toxic in the dark, but potently cytotoxic to cancer cells when irradiated by visible light …