Overcoming barriers by local drug delivery with liposomes

SG Antimisiaris, A Marazioti, M Kannavou… - Advanced drug delivery …, 2021 - Elsevier
Localized or topical administration of drugs may be considered as a potential approach for
overcoming the problems caused by the various biological barriers encountered in drug …

Liposomes in drug delivery: progress and limitations

A Sharma, US Sharma - International journal of pharmaceutics, 1997 - Elsevier
Liposomes are microparticulate lipoidal vesicles which are under extensive investigation as
drug carriers for improving the delivery of therapeutic agents. Due to new developments in …

Pharmaceutical liposomal delivery—specific considerations of innovation and challenges

T Peng, W Xu, Q Li, Y Ding, Y Huang - Biomaterials science, 2023 - pubs.rsc.org
Liposomal technology has been widely used in the pharmaceutical field for the preparation
of nano-sized drug delivery systems based on natural or synthetic lipids. Liposomes …

[HTML][HTML] The use of lipid-based nanocarriers for targeted pain therapies

S Hua, SY Wu - Frontiers in pharmacology, 2013 - frontiersin.org
Sustained delivery of analgesic agents at target sites remains a critical issue for effective
pain management. The use of nanocarriers has been reported to facilitate effective delivery …

Liposomes as a topical drug delivery system

K Egbaria, N Weiner - Advanced drug delivery reviews, 1990 - Elsevier
In the past decade, liposomal formulations have been extensively employed to enhance the
efficiency of drug delivery via several routes of administration. In a number of instances …

Pharmacokinetics and in vivo drug release rates in liposomal nanocarrier development

DC Drummond, CO Noble, ME Hayes, JW Park… - Journal of …, 2008 - Elsevier
Liposomes represent a widely varied and malleable class of drug carriers generally
characterized by the presence of one or more amphiphile bilayers enclosing an interior …

[HTML][HTML] Advances and challenges of liposome assisted drug delivery

L Sercombe, T Veerati, F Moheimani, SY Wu… - Frontiers in …, 2015 - frontiersin.org
The application of liposomes to assist drug delivery has already had a major impact on
many biomedical areas. They have been shown to be beneficial for stabilizing therapeutic …

Pharmaceutical liposomal drug delivery: a review of new delivery systems and a look at the regulatory landscape

C Zylberberg, S Matosevic - Drug delivery, 2016 - Taylor & Francis
Liposomes were the first nanoscale drug to be approved for clinical use in 1995. Since then,
the technology has grown considerably, and pioneering recent work in liposome-based …

Liposomes as carriers of hydrophilic small molecule drugs: strategies to enhance encapsulation and delivery

JO Eloy, MC de Souza, R Petrilli, JPA Barcellos… - Colloids and surfaces B …, 2014 - Elsevier
Although hydrophilic small molecule drugs are widely used in the clinic, their rapid
clearance, suboptimal biodistribution, low intracellular absorption and toxicity can limit their …

New developments in liposomal drug delivery

BS Pattni, VV Chupin, VP Torchilin - Chemical reviews, 2015 - ACS Publications
New Developments in Liposomal Drug Delivery | Chemical Reviews ACS ACS Publications
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