[HTML][HTML] Prognostic importance of C-KIT mutations in core binding factor acute myeloid leukemia: a systematic review
Objective/background Acute myeloid leukemia (AML) is defined as leukemic blast
reproduction in bone marrow. Chromosomal abnormalities form different subgroups with …
reproduction in bone marrow. Chromosomal abnormalities form different subgroups with …
Prevalence and prognostic significance of c-KIT mutations in core binding factor acute myeloid leukemia: a comprehensive large-scale study from a single Chinese …
YZ Qin, HH Zhu, Q Jiang, H Jiang, LP Zhang, LP Xu… - Leukemia research, 2014 - Elsevier
To clarify the prevalence and prognostic significance of c-KIT mutations in patients with core
binding factor acute myeloid leukemia (CBF-AML), a total of 351 patients who were …
binding factor acute myeloid leukemia (CBF-AML), a total of 351 patients who were …
[HTML][HTML] Core binding factor acute myeloid leukaemia and c-KIT mutations
L Riera, F Marmont, D Toppino… - Oncology …, 2013 - spandidos-publications.com
Core binding factor (CBF) acute myeloid leukaemia (AML) represents 5-8% of all AMLs and
has a relatively favourable prognosis. However, activating c-KIT mutations are reported to be …
has a relatively favourable prognosis. However, activating c-KIT mutations are reported to be …
[HTML][HTML] Incidences and prognostic impact of c-KIT, WT1, CEBPA, and CBL mutations, and mutations associated with epigenetic modification in core binding factor …
SH Park, HJ Lee, IS Kim, JE Kang… - Annals of laboratory …, 2015 - synapse.koreamed.org
Background To identify potential molecular prognostic markers in core binding factor (CBF)
AML, we analyzed incidences and prognostic impacts of mutations in c-KIT, WT1, CEBPA …
AML, we analyzed incidences and prognostic impacts of mutations in c-KIT, WT1, CEBPA …
Prognostic impact of c-KIT mutations in core binding factor acute myeloid leukemia
SH Park, HS Chi, SK Min, BG Park, S Jang, CJ Park - Leukemia research, 2011 - Elsevier
This study sought to define the prognostic impact of c-KIT mutations in core binding factor
acute myeloid leukemia (CBF AML) patients. A total of 116 patients diagnosed as CBF AML …
acute myeloid leukemia (CBF AML) patients. A total of 116 patients diagnosed as CBF AML …
[HTML][HTML] Prognostic Significance of KIT Mutations in Core-Binding Factor Acute Myeloid Leukemia: A Systematic Review and Meta-Analysis
W Chen, H Xie, H Wang, L Chen, Y Sun, Z Chen, Q Li - Plos one, 2016 - journals.plos.org
The prognostic significance of KIT mutations in core-binding factor acute myeloid leukemia
(CBF-AML), including inv (16) and t (8; 21) AML, is uncertain. We performed a systematic …
(CBF-AML), including inv (16) and t (8; 21) AML, is uncertain. We performed a systematic …
Core-binding factor acute myeloid leukemia in pediatric patients enrolled in the AIEOP AML 2002/01 trial: screening and prognostic impact of c-KIT mutations
The proto-oncogene c-KIT, which encodes a receptor for stem cell factor (SCF), belongs to
the type-III receptor of the tyrosine kinase subfamily and is characterized by five extracellular …
the type-III receptor of the tyrosine kinase subfamily and is characterized by five extracellular …
Prognostic impact of c-KIT mutations in core binding factor leukemias: an Italian retrospective study
Distinct forms of tyrosine kinase domain (TKD), juxtamembrane domain, exon 8, and internal
tandem duplication (ITD) mutations of c-KIT, were observed in about 46% of core binding …
tandem duplication (ITD) mutations of c-KIT, were observed in about 46% of core binding …
D816 mutation of the KIT gene in core binding factor acute myeloid leukemia is associated with poorer prognosis than other KIT gene mutations
S Yui, S Kurosawa, H Yamaguchi, H Kanamori… - Annals of …, 2017 - Springer
The clinical impact of KIT mutations in core binding factor acute myeloid leukemia (CBF-
AML) is still unclear. In the present study, we analyzed the prognostic significance of each …
AML) is still unclear. In the present study, we analyzed the prognostic significance of each …
[HTML][HTML] D816V mutation in the KIT gene activation loop has greater cell-proliferative and anti-apoptotic ability than N822K mutation in core-binding factor acute …
I Omori, H Yamaguchi, K Miyake, N Miyake… - Experimental …, 2017 - Elsevier
In core-binding factor acute myeloid leukemia (CBF-AML), there have been conflicting
reports regarding the status as an unfavorable prognostic factor of mutation in the KIT gene …
reports regarding the status as an unfavorable prognostic factor of mutation in the KIT gene …