Long-chain acyl-CoA synthetases (ACSLs) catalyze the thioesterification of long-chain FAs
into their acyl-CoA derivatives. Purified ACSL4 is an arachidonic acid (20: 4)-preferring …

Acyl coenzyme A synthetase long-chain family members (ACSLs) are a family of enzymes
that convert long-chain free fatty acids into their acyl-CoAs and play an important role in fatty …

The activation of long-chain free fatty acids is the first step reaction of their usage in the cells
and tissues, which are catalyzed by a family of enzymes called acyl-coenzyme A …

Long-chain acyl-coenzyme A synthetases (ACSLs) are a family of enzymes that convert free
long-chain fatty acids into their acyl-coenzyme A (CoA) forms. ACSL4, belonging to the …

Long chain acyl-CoA synthetase (ACSL) catalyzes the initial step in long chain fatty acid
metabolism. Of the five mammalian ACSL isoforms cloned and characterized, ACSL5 is the …

Because the signaling eicosanoids, epoxyeicosatrienoic acids (EETs) and HETEs, are
esterified to membrane phospholipids, we asked which long-chain acyl-CoA synthetase …

Objective The family of acyl-CoA synthetase enzymes (ACSL) activates fatty acids within
cells to generate long chain fatty acyl CoA (FACoA). The differing metabolic fates of FACoAs …

In mammals, a family of five acyl-CoA synthetases (ACSLs), each the product of a separate
gene, activates long chain fatty acids to form acyl-CoAs. Because the ACSL isoforms have …

Chronic inflammation contributes to cardiovascular disease. Increased levels of the
inflammatory cytokine, TNF-α, are often present in conditions associated with cardiovascular …

Long chain acyl-CoA synthetases (ACSL) activate fatty acids (FA) and provide substrates for
both anabolic and catabolic pathways. We have hypothesized that each of the five ACSL …