[PDF][PDF] Synthesis, structural characterization of some pyrazolo [1-5a] pyrimidine and imidazo [1, 2-b]-pyrazole derivatives as anticancer activity

U Fathy, AA Abu-Hashem, RS Gouhar, HM Awad… - Rasyan J …, 2021 - researchgate.net
For anticancer cell line evaluation, a new sequence of pyrazolo [1-5a] pyrimidine and
imidazo [1, 2-b] pyrazole derivatives were synthesized. The reaction of 5-aminopyrazolo with …

Synthesis and antitumor activity of novel pyrazolo [1, 5-a] pyrimidine derivatives

MM El-Enany, MM Kamel, OM Khalil… - European Journal of …, 2011 - eurjchem.com
A novel series of pyrazolo [1, 5-a] pyrimidine-3-carbonitriles substituted with 7-amino, 7-
substituted amino and 5-substituted amino groups was synthesized. Some of the newly …

Synthesis and Anti‐tumor Activities of Novel Pyrazolo[1,5‐a]pyrimidines

J Li, YF Zhao, XL Zhao, XY Yuan… - Archiv der Pharmazie …, 2006 - Wiley Online Library
A series of novel pyrazolo [1, 5‐a] pyrimidines were designed and synthesized in order to
find novel potent anti‐tumor compounds. The structures of all the compounds were …

[PDF][PDF] Synthesis, reactivity and antitumor activity of some new pyrazolo [3, 4-d] pyrimidine and their triazole derivatives

IF Nassar, SAE Assaly - Der Pharma Chemica, 2011 - academia.edu
ABSTRACT Some pyrazolo [3, 4-d] pyrimidines derivatives and their triazole derivatives
were synthesized starting from p-toluene sulfonyl hydrazide 1 by reaction with different …

[HTML][HTML] Synthesis, In Vitro Antimicrobial and Cytotoxic Activities of Some New Pyrazolo[1,5-a]pyrimidine Derivatives

AM Fouda, HAS Abbas, EH Ahmed, AA Shati, MY Alfaifi… - Molecules, 2019 - mdpi.com
A new series of pyrazole 4–7 and pyrazolo [1, 5-a] pyrimidine 8–13 were synthesized by
using a simple, efficient procedure, and screened for their in-vitro antimicrobial and …

Synthesis and antitumor activity of some new pyrazolo [3, 4-d] pyrimidine and pyrazolo [3, 4-b] pyridine derivatives

E Abdel-Latif, S Abdel-Fattah, HE Gaffer… - Egyptian Journal of …, 2016 - Taylor & Francis
A new series of pyrazolo [3, 4-d] pyrimidine-3-carbonitrile and pyrazolo [3, 4-b] pyridine-3-
carbonitrile derivatives was synthesized by the reaction of 5-amino-1-tosyl-1 H-pyrazole-3, 4 …

Design, synthesis and anti-cancer evaluation of a novel series of pyrazolo [1, 5-a] pyrimidine substituted diamide derivatives

AK Ajeesh Kumar, YD Bodke, PS Lakra… - Medicinal Chemistry …, 2017 - Springer
A novel series of pyrazolo [1, 5-a] pyrimidine substituted diamides has been designed and
synthesized using a linear mode multistep synthesis. The synthesized compounds were …

Synthesis, cytotoxicity of some pyrazoles and pyrazolo [1, 5-a] pyrimidines bearing benzothiazole moiety and investigation of their mechanism of action

EM Husseiny - Bioorganic Chemistry, 2020 - Elsevier
A novel series of pyrazoles and pyrazolo [1, 5-a] pyrimidines bearing benzothiazole moiety
were designed and synthesized. Chemical structures were confirmed by spectral data and …

Synthesis and biological evaluation of aryl derivatives of isoxazole pyrazolo [1, 5-a] pyrimidines as anticancer agents

DN Bhogireddy, SR Surapureddi, T Syed… - Synthetic …, 2022 - Taylor & Francis
A new library of different substituted aryl derivatives of isoxazole-pyrazolo [1, 5-a] pyrimidine
(10a–j) were prepared, confirmed their structures by 1HNMR, 13CNMR and mass spectral …

Facile Synthesis and In‐Vitro Antitumor Activity of Some Pyrazolo[3,4‐b]pyridines and Pyrazolo[1,5‐a]pyrimidines Linked to a Thiazolo[3,2‐a]benzimidazole Moiety

HA Abdel‐Aziz, TS Saleh… - Archiv der Pharmazie …, 2010 - Wiley Online Library
Abstract The key precursor E‐3‐(N, N‐dimethylamino)‐1‐(3‐methylthiazolo [3, 2‐a]
benzimidazol‐2‐yl) prop‐2‐en‐1‐one 4 was synthesized in good yield using Gold's reagent …